Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component

Herpes simplex virus type-2 (HSV-2) belongs to the α-herpesvirinae subfamily and is a sexually transmitted virus that causes genital ulcer disease. Here the authors present the 3.75 Å cryo-EM structure of the HSV-2 C-capsid with capsid-vertex-specific component and describe α-herpesvirus-specific st...

Full description

Bibliographic Details
Main Authors: Jialing Wang, Shuai Yuan, Dongjie Zhu, Hao Tang, Nan Wang, Wenyuan Chen, Qiang Gao, Yuhua Li, Junzhi Wang, Hongrong Liu, Xinzheng Zhang, Zihe Rao, Xiangxi Wang
Format: Article
Language:English
Published: Nature Portfolio 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06078-4
_version_ 1828903257171296256
author Jialing Wang
Shuai Yuan
Dongjie Zhu
Hao Tang
Nan Wang
Wenyuan Chen
Qiang Gao
Yuhua Li
Junzhi Wang
Hongrong Liu
Xinzheng Zhang
Zihe Rao
Xiangxi Wang
author_facet Jialing Wang
Shuai Yuan
Dongjie Zhu
Hao Tang
Nan Wang
Wenyuan Chen
Qiang Gao
Yuhua Li
Junzhi Wang
Hongrong Liu
Xinzheng Zhang
Zihe Rao
Xiangxi Wang
author_sort Jialing Wang
collection DOAJ
description Herpes simplex virus type-2 (HSV-2) belongs to the α-herpesvirinae subfamily and is a sexually transmitted virus that causes genital ulcer disease. Here the authors present the 3.75 Å cryo-EM structure of the HSV-2 C-capsid with capsid-vertex-specific component and describe α-herpesvirus-specific structural features.
first_indexed 2024-12-13T16:30:34Z
format Article
id doaj.art-ead2107e90e1403db28d0bda54171e5f
institution Directory Open Access Journal
issn 2041-1723
language English
last_indexed 2024-12-13T16:30:34Z
publishDate 2018-09-01
publisher Nature Portfolio
record_format Article
series Nature Communications
spelling doaj.art-ead2107e90e1403db28d0bda54171e5f2022-12-21T23:38:31ZengNature PortfolioNature Communications2041-17232018-09-019111010.1038/s41467-018-06078-4Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific componentJialing Wang0Shuai Yuan1Dongjie Zhu2Hao Tang3Nan Wang4Wenyuan Chen5Qiang Gao6Yuhua Li7Junzhi Wang8Hongrong Liu9Xinzheng Zhang10Zihe Rao11Xiangxi Wang12National Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of ScienceNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of ScienceNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of ScienceCollege of Physics and Information Science, Synergetic Innovation Center for Quantum Effects and Applications, Key Laboratory of Low-dimensional Quantum Structures, and Quantum Control of the Ministry of Education, Hunan Normal UniversityNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of ScienceCollege of Physics and Information Science, Synergetic Innovation Center for Quantum Effects and Applications, Key Laboratory of Low-dimensional Quantum Structures, and Quantum Control of the Ministry of Education, Hunan Normal UniversityNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of ScienceNational Institutes for Food and Drug ControlNational Institutes for Food and Drug ControlCollege of Physics and Information Science, Synergetic Innovation Center for Quantum Effects and Applications, Key Laboratory of Low-dimensional Quantum Structures, and Quantum Control of the Ministry of Education, Hunan Normal UniversityNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of ScienceNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of ScienceNational Laboratory of Macromolecules, Institute of Biophysics, Chinese Academy of ScienceHerpes simplex virus type-2 (HSV-2) belongs to the α-herpesvirinae subfamily and is a sexually transmitted virus that causes genital ulcer disease. Here the authors present the 3.75 Å cryo-EM structure of the HSV-2 C-capsid with capsid-vertex-specific component and describe α-herpesvirus-specific structural features.https://doi.org/10.1038/s41467-018-06078-4
spellingShingle Jialing Wang
Shuai Yuan
Dongjie Zhu
Hao Tang
Nan Wang
Wenyuan Chen
Qiang Gao
Yuhua Li
Junzhi Wang
Hongrong Liu
Xinzheng Zhang
Zihe Rao
Xiangxi Wang
Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component
Nature Communications
title Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component
title_full Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component
title_fullStr Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component
title_full_unstemmed Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component
title_short Structure of the herpes simplex virus type 2 C-capsid with capsid-vertex-specific component
title_sort structure of the herpes simplex virus type 2 c capsid with capsid vertex specific component
url https://doi.org/10.1038/s41467-018-06078-4
work_keys_str_mv AT jialingwang structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT shuaiyuan structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT dongjiezhu structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT haotang structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT nanwang structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT wenyuanchen structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT qianggao structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT yuhuali structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT junzhiwang structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT hongrongliu structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT xinzhengzhang structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT ziherao structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent
AT xiangxiwang structureoftheherpessimplexvirustype2ccapsidwithcapsidvertexspecificcomponent