Comparison of Exosomes Derived from Non- and Gamma-Irradiated Melanoma Cancer Cells as a Potential Antigenic and Immunogenic Source for Dendritic Cell-Based Immunotherapeutic Vaccine

Comparison of Exosomes Derived from Non- and Gamma-Irradiated Melanoma Cancer Cells as a Potential Antigenic and Immunogenic Source for Dendritic Cell-Based Immunotherapeutic Vaccine

Cancer cells can secrete exosomes under various stressful conditions, whose functions are involved in the delivery of various biologically active materials into host cells and/or modulation of host immune responses. Therefore, an improved understanding of the immunological interventions that stress-...

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Bibliographic Details
Main Authors: Woo Sik Kim, DaeSeong Choi, Ji Min Park, Ha-Yeon Song, Ho Seong Seo, Dong-Eun Lee, Eui-Baek Byun
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Vaccines
Subjects:
melanoma cancer exosome
gamma irradiation
dendritic cells
tumor antigen-specific multifunctional T cells
vaccine
Online Access:https://www.mdpi.com/2076-393X/8/4/699

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