HIV Productively Infects Highly Differentiated and Exhausted CD4+ T Cells During AIDS

HIV Productively Infects Highly Differentiated and Exhausted CD4+ T Cells During AIDS

Background: Throughout HIV infection, productively infected cells generate billions of viral particles and are thus responsible for body-wide HIV dissemination, but their phenotype during AIDS is unknown. As AIDS is associated with immunological changes, analyzing the phenotype of productively infe...

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Bibliographic Details
Main Authors: Clayton Faua, Axel Ursenbach, Anne Fuchs, Stéphanie Caspar, Frédéric Jegou, Yvon Ruch, Baptiste Hoellinger, Elodie Laugel, Aurélie Velay, David Rey, Samira Fafi-Kremer, Pierre Gantner
Format: Article
Language:English
Published: Case Western Reserve University 2024-02-01
Series:Pathogens and Immunity
Subjects:
AIDS
recent infection
productively infected cells
phenotype
exhaustion
Online Access:https://www.paijournal.com/index.php/paijournal/article/view/638

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