Formulation, optimization and evaluation of ocular gel containing nebivolol Hcl-loaded ultradeformable spanlastics nanovesicles: In vitro and in vivo studies
The study aims to improve the ocular delivery of Nebivolol HCL (NBV) belonging to the Biopharmaceutics classification system (BCSII) by using spanlastic nanovesicles (SNVs) for ophthalmic delivery and incorporating them into hydroxypropyl methylcellulose gel with ketorolac tromethamine (KET) as an a...
Main Authors: | Mohamed Yasser, Eman E. El Naggar, Nehal Elfar, Mahmoud H. Teaima, Mohamed A. El-Nabarawi, Sammar Fathy Elhabal |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2024-06-01
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Series: | International Journal of Pharmaceutics: X |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2590156723000725 |
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