Prevalence and genetic basis of tooth agenesis
Tooth agenesis or hypodontia is one of the most common anomalies of the human dentition, characterized by the developmental absence of one or more teeth. Many studies have reported that the prevalence of congenital absence of permanent teeth varies from 3% to 11% among European and Asian populations...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Elsevier
2009-05-01
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| Series: | Japanese Dental Science Review |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1882761608000859 |
| _version_ | 1819293298635833344 |
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| author | Takehiko Shimizu Takahide Maeda |
| author_facet | Takehiko Shimizu Takahide Maeda |
| author_sort | Takehiko Shimizu |
| collection | DOAJ |
| description | Tooth agenesis or hypodontia is one of the most common anomalies of the human dentition, characterized by the developmental absence of one or more teeth. Many studies have reported that the prevalence of congenital absence of permanent teeth varies from 3% to 11% among European and Asian populations. Recent advances in the fields of molecular biology and human genetics have improved our understanding of the cause of tooth agenesis. In this review, we assess the previous literature on prevalence of tooth agenesis comparing the Japanese with other racial populations, and describe the recent genetic studies associated with hypodontia in human and mouse models. |
| first_indexed | 2024-12-24T04:08:12Z |
| format | Article |
| id | doaj.art-ead54a120cf245528173e06b74565564 |
| institution | Directory Open Access Journal |
| issn | 1882-7616 |
| language | English |
| last_indexed | 2024-12-24T04:08:12Z |
| publishDate | 2009-05-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Japanese Dental Science Review |
| spelling | doaj.art-ead54a120cf245528173e06b745655642022-12-21T17:16:09ZengElsevierJapanese Dental Science Review1882-76162009-05-01451525810.1016/j.jdsr.2008.12.001Prevalence and genetic basis of tooth agenesisTakehiko ShimizuTakahide MaedaTooth agenesis or hypodontia is one of the most common anomalies of the human dentition, characterized by the developmental absence of one or more teeth. Many studies have reported that the prevalence of congenital absence of permanent teeth varies from 3% to 11% among European and Asian populations. Recent advances in the fields of molecular biology and human genetics have improved our understanding of the cause of tooth agenesis. In this review, we assess the previous literature on prevalence of tooth agenesis comparing the Japanese with other racial populations, and describe the recent genetic studies associated with hypodontia in human and mouse models.http://www.sciencedirect.com/science/article/pii/S1882761608000859Tooth agenesisHypodontiaOligodontiaEpidemiologyEtiologyGenetic |
| spellingShingle | Takehiko Shimizu Takahide Maeda Prevalence and genetic basis of tooth agenesis Japanese Dental Science Review Tooth agenesis Hypodontia Oligodontia Epidemiology Etiology Genetic |
| title | Prevalence and genetic basis of tooth agenesis |
| title_full | Prevalence and genetic basis of tooth agenesis |
| title_fullStr | Prevalence and genetic basis of tooth agenesis |
| title_full_unstemmed | Prevalence and genetic basis of tooth agenesis |
| title_short | Prevalence and genetic basis of tooth agenesis |
| title_sort | prevalence and genetic basis of tooth agenesis |
| topic | Tooth agenesis Hypodontia Oligodontia Epidemiology Etiology Genetic |
| url | http://www.sciencedirect.com/science/article/pii/S1882761608000859 |
| work_keys_str_mv | AT takehikoshimizu prevalenceandgeneticbasisoftoothagenesis AT takahidemaeda prevalenceandgeneticbasisoftoothagenesis |