HOXC4 up-regulates NF-κB signaling and promotes the cell proliferation to drive development of human hematopoiesis, especially CD43+ cells

HOXC4 up-regulates NF-κB signaling and promotes the cell proliferation to drive development of human hematopoiesis, especially CD43+ cells

Abstract. The hematopoietic function of HOXC4 has not been extensively investigated. Our research indicated that induction of HOXC4 in co-culture system from D10 significantly promoted productions of most hematopoietic progenitor cells. CD34−CD43+ cells could be clearly classified into CD34−CD43low...

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Bibliographic Details
Main Authors: Jiahui Zeng, Wencui Sun, Jing Chang, Danying Yi, Lijiao Zhu, Yonggang Zhang, Xu Pan, Ya Zhou, Mowen Lai, Guohui Bian, Qiongxiu Zhou, Jiaxin Liu, Bo Chen, Feng Ma
Format: Article
Language:English
Published: Wolters Kluwer Health 2020-10-01
Series:Blood Science
Online Access:http://journals.lww.com/10.1097/BS9.0000000000000054

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