Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, Afghanistan
Mahmoodullah Azimi,1 Wazhma Masoom Dehzad,1 Mohammad Asif Atiq,1 Barin Bahain,1 Abdullah Asady2 1Department of Clinical Pharmacology, Kabul University of Medical Sciences, Kabul, Afghanistan; 2Department of Microbiology, Kabul University of Medical Sciences, Kabul, AfghanistanCorrespondence: Abdulla...
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| Format: | Article |
| Language: | English |
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Dove Medical Press
2021-10-01
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| Series: | Infection and Drug Resistance |
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| Online Access: | https://www.dovepress.com/adverse-effects-of-the-covid-19-vaccine-reported-by-lecturers-and-staf-peer-reviewed-fulltext-article-IDR |
| _version_ | 1818407316599341056 |
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| author | Azimi M Dehzad WM Atiq MA Bahain B Asady A |
| author_facet | Azimi M Dehzad WM Atiq MA Bahain B Asady A |
| author_sort | Azimi M |
| collection | DOAJ |
| description | Mahmoodullah Azimi,1 Wazhma Masoom Dehzad,1 Mohammad Asif Atiq,1 Barin Bahain,1 Abdullah Asady2 1Department of Clinical Pharmacology, Kabul University of Medical Sciences, Kabul, Afghanistan; 2Department of Microbiology, Kabul University of Medical Sciences, Kabul, AfghanistanCorrespondence: Abdullah AsadyDepartment of Microbiology, Kabul University of Medical Sciences, Kabul, AfghanistanTel +93731087928Email asady_abdullah@yahoo.comPurpose: To evaluate the occurrence, extent, and severity of adverse reactions associated with the vaccine of COVID-19 (ChAdOx1 nCoV-19 vaccine or AstraZeneca) among Kabul University of Medical Sciences staff.Patients and Methods: A retrospective observational, interview-based study was conducted from 4 to 20 April, 2021, to evaluate the adverse reactions associated with the vaccine of COVID-19 (ChAdOx1 nCoV-19 vaccine or AstraZeneca) among the staff and lecturers of the Kabul University of Medical Sciences, Kabul, Afghanistan. Participants were interviewed following the administration of the first dose of the AstraZeneca vaccines. They were asked to report any adverse reactions that occurred within 8– 10 days after vaccination. The frequency, duration, severity, and outcome of the reactions were recorded. Association of the adverse reactions was analysed with the ages of participants and previous infection with SARS CoV-2.Results: The most common adverse reactions reported by the participants were muscle pain (68.3%), local pain (58.8%) at the site of injection (68.3%), fever (66.3%) and fatigue (66.3%). Almost half of the respondents reported chills, joint pain and headache after receiving the first shot of the vaccine. The frequency of adverse reactions was higher in participants aged 40 years or less, and in those previously infected with SARS CoV-2. The severity of most adverse reactions was mild to moderate. No serious case or death was reported.Conclusion: The adverse reactions reported by the participants were mild to moderate in severity, and for a short duration. The findings of this study help us to address the vaccine hesitancy caused by worries about severe adverse effects associated with the COVID-19 vaccine.Keywords: adverse effects, COVID-19, vaccine, ChAdOx1 nCoV-19, AstraZeneca |
| first_indexed | 2024-12-14T09:25:54Z |
| format | Article |
| id | doaj.art-ead681b384db4e86991eb2a18d80f2a8 |
| institution | Directory Open Access Journal |
| issn | 1178-6973 |
| language | English |
| last_indexed | 2024-12-14T09:25:54Z |
| publishDate | 2021-10-01 |
| publisher | Dove Medical Press |
| record_format | Article |
| series | Infection and Drug Resistance |
| spelling | doaj.art-ead681b384db4e86991eb2a18d80f2a82022-12-21T23:08:11ZengDove Medical PressInfection and Drug Resistance1178-69732021-10-01Volume 144077408369401Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, AfghanistanAzimi MDehzad WMAtiq MABahain BAsady AMahmoodullah Azimi,1 Wazhma Masoom Dehzad,1 Mohammad Asif Atiq,1 Barin Bahain,1 Abdullah Asady2 1Department of Clinical Pharmacology, Kabul University of Medical Sciences, Kabul, Afghanistan; 2Department of Microbiology, Kabul University of Medical Sciences, Kabul, AfghanistanCorrespondence: Abdullah AsadyDepartment of Microbiology, Kabul University of Medical Sciences, Kabul, AfghanistanTel +93731087928Email asady_abdullah@yahoo.comPurpose: To evaluate the occurrence, extent, and severity of adverse reactions associated with the vaccine of COVID-19 (ChAdOx1 nCoV-19 vaccine or AstraZeneca) among Kabul University of Medical Sciences staff.Patients and Methods: A retrospective observational, interview-based study was conducted from 4 to 20 April, 2021, to evaluate the adverse reactions associated with the vaccine of COVID-19 (ChAdOx1 nCoV-19 vaccine or AstraZeneca) among the staff and lecturers of the Kabul University of Medical Sciences, Kabul, Afghanistan. Participants were interviewed following the administration of the first dose of the AstraZeneca vaccines. They were asked to report any adverse reactions that occurred within 8– 10 days after vaccination. The frequency, duration, severity, and outcome of the reactions were recorded. Association of the adverse reactions was analysed with the ages of participants and previous infection with SARS CoV-2.Results: The most common adverse reactions reported by the participants were muscle pain (68.3%), local pain (58.8%) at the site of injection (68.3%), fever (66.3%) and fatigue (66.3%). Almost half of the respondents reported chills, joint pain and headache after receiving the first shot of the vaccine. The frequency of adverse reactions was higher in participants aged 40 years or less, and in those previously infected with SARS CoV-2. The severity of most adverse reactions was mild to moderate. No serious case or death was reported.Conclusion: The adverse reactions reported by the participants were mild to moderate in severity, and for a short duration. The findings of this study help us to address the vaccine hesitancy caused by worries about severe adverse effects associated with the COVID-19 vaccine.Keywords: adverse effects, COVID-19, vaccine, ChAdOx1 nCoV-19, AstraZenecahttps://www.dovepress.com/adverse-effects-of-the-covid-19-vaccine-reported-by-lecturers-and-staf-peer-reviewed-fulltext-article-IDRadverse effectscovid-19vaccinechadox1 ncov-19astrazeneca |
| spellingShingle | Azimi M Dehzad WM Atiq MA Bahain B Asady A Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, Afghanistan Infection and Drug Resistance adverse effects covid-19 vaccine chadox1 ncov-19 astrazeneca |
| title | Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, Afghanistan |
| title_full | Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, Afghanistan |
| title_fullStr | Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, Afghanistan |
| title_full_unstemmed | Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, Afghanistan |
| title_short | Adverse Effects of the COVID-19 Vaccine Reported by Lecturers and Staff of Kabul University of Medical Sciences, Kabul, Afghanistan |
| title_sort | adverse effects of the covid 19 vaccine reported by lecturers and staff of kabul university of medical sciences kabul afghanistan |
| topic | adverse effects covid-19 vaccine chadox1 ncov-19 astrazeneca |
| url | https://www.dovepress.com/adverse-effects-of-the-covid-19-vaccine-reported-by-lecturers-and-staf-peer-reviewed-fulltext-article-IDR |
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