Epigenetic phenotype of plasma cell-free DNA in the prediction of early-onset preeclampsia

Epigenetic phenotype of plasma cell-free DNA in the prediction of early-onset preeclampsia

AbstractBackground In the current study, we sought to characterise the methylation haplotypes and nucleosome positioning patterns of placental DNA and plasma cell-free DNA of pregnant women with early-onset preeclampsia using whole genome bisulphite sequencing (WGBS) and methylation capture bisulphi...

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Bibliographic Details
Main Authors: Wei He, Yi Zhang, Kai Wu, Yunan Wang, Xin Zhao, Lijuan Lv, Congmian Ren, Jiaqi Lu, Jiexia Yang, Aihua Yin, Guocheng Liu
Format: Article
Language:English
Published: Taylor & Francis Group 2023-12-01
Series:Journal of Obstetrics and Gynaecology
Subjects:
Early-onset preeclampsia
cell-free DNA
non-invasive prenatal testing
DNA methylation
nucleosome
Online Access:https://www.tandfonline.com/doi/10.1080/01443615.2023.2282100

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