Introduction of a Simple and Minimally Invasive Approach for Access to Epidural Space in Cat
Background: Although various studied have been done to improve therapeutic strategies in resolving spinal cord injuries, robust clinical treatment is not yet available. Developing a standard animal model is essential to achieve effective treatment for such injuries. The present study was performed t...
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| Format: | Article |
| Language: | English |
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Shahid Beheshti University of Medical Sciences
2021-07-01
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| Series: | International Clinical Neuroscience Journal |
| Subjects: | |
| Online Access: | https://journals.sbmu.ac.ir/neuroscience/article/view/34724/27354 |
| _version_ | 1818434584774180864 |
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| author | Asma Asadian Mirsepehr Pedram Mohamad Mehdi Dehghan Javad Sadeghinejad Majid Masoudifard Saeide Eftekhari Roja Ebrahimi |
| author_facet | Asma Asadian Mirsepehr Pedram Mohamad Mehdi Dehghan Javad Sadeghinejad Majid Masoudifard Saeide Eftekhari Roja Ebrahimi |
| author_sort | Asma Asadian |
| collection | DOAJ |
| description | Background: Although various studied have been done to improve therapeutic strategies in resolving spinal cord injuries, robust clinical treatment is not yet available. Developing a standard animal model is essential to achieve effective treatment for such injuries. The present study was performed to introduce a simple, applicable, and minimally invasive approach for access to epidural space in cats. Methods: We used a percutaneous approach from the lumbosacral junction for stainless steel cannula insertion to the epidural space without fluoroscopy. CT scan, conventional magnetic resonance imaging (MRI), tractography, and behavioral evaluation were used to assess the correct position of the cannula and the neurological condition of the animal. Results: MRI results showed no significant change in signal intensity index of neural structures under lumbosacral junction. These observations are further supported by tractography, and also behavioral examination during the study. Conclusion: We found that the percutaneous approach from the lumbosacral junction is a simple and applicable approach that has no side effects and artifact formation in MRI evaluation. |
| first_indexed | 2024-12-14T16:39:19Z |
| format | Article |
| id | doaj.art-eadce122836c4c65b993db083346df47 |
| institution | Directory Open Access Journal |
| issn | 2383-1871 2383-2096 |
| language | English |
| last_indexed | 2024-12-14T16:39:19Z |
| publishDate | 2021-07-01 |
| publisher | Shahid Beheshti University of Medical Sciences |
| record_format | Article |
| series | International Clinical Neuroscience Journal |
| spelling | doaj.art-eadce122836c4c65b993db083346df472022-12-21T22:54:22ZengShahid Beheshti University of Medical SciencesInternational Clinical Neuroscience Journal2383-18712383-20962021-07-018311812310.34172/icnj.2021.25icnj-8178Introduction of a Simple and Minimally Invasive Approach for Access to Epidural Space in CatAsma Asadian0Mirsepehr Pedram1Mohamad Mehdi Dehghan2Javad Sadeghinejad3Majid Masoudifard4Saeide Eftekhari5Roja Ebrahimi6Department of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, IranDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, IranDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, IranDepartment of Basic Sciences, Faculty of Veterinary Medicine, University of Tehran, IranDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, IranDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, IranDepartment of Surgery and Radiology, Faculty of Veterinary Medicine, University of Tehran, Tehran, IranBackground: Although various studied have been done to improve therapeutic strategies in resolving spinal cord injuries, robust clinical treatment is not yet available. Developing a standard animal model is essential to achieve effective treatment for such injuries. The present study was performed to introduce a simple, applicable, and minimally invasive approach for access to epidural space in cats. Methods: We used a percutaneous approach from the lumbosacral junction for stainless steel cannula insertion to the epidural space without fluoroscopy. CT scan, conventional magnetic resonance imaging (MRI), tractography, and behavioral evaluation were used to assess the correct position of the cannula and the neurological condition of the animal. Results: MRI results showed no significant change in signal intensity index of neural structures under lumbosacral junction. These observations are further supported by tractography, and also behavioral examination during the study. Conclusion: We found that the percutaneous approach from the lumbosacral junction is a simple and applicable approach that has no side effects and artifact formation in MRI evaluation.https://journals.sbmu.ac.ir/neuroscience/article/view/34724/27354spinal cord injurypercutaneous approachlumbosacral junctioncatminimally invasive |
| spellingShingle | Asma Asadian Mirsepehr Pedram Mohamad Mehdi Dehghan Javad Sadeghinejad Majid Masoudifard Saeide Eftekhari Roja Ebrahimi Introduction of a Simple and Minimally Invasive Approach for Access to Epidural Space in Cat International Clinical Neuroscience Journal spinal cord injury percutaneous approach lumbosacral junction cat minimally invasive |
| title | Introduction of a Simple and Minimally Invasive Approach for Access to Epidural Space in Cat |
| title_full | Introduction of a Simple and Minimally Invasive Approach for Access to Epidural Space in Cat |
| title_fullStr | Introduction of a Simple and Minimally Invasive Approach for Access to Epidural Space in Cat |
| title_full_unstemmed | Introduction of a Simple and Minimally Invasive Approach for Access to Epidural Space in Cat |
| title_short | Introduction of a Simple and Minimally Invasive Approach for Access to Epidural Space in Cat |
| title_sort | introduction of a simple and minimally invasive approach for access to epidural space in cat |
| topic | spinal cord injury percutaneous approach lumbosacral junction cat minimally invasive |
| url | https://journals.sbmu.ac.ir/neuroscience/article/view/34724/27354 |
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