Modelling reassurances of clinicians with hidden Markov models

Abstract Background A key element in the interaction between clinicians and patients with cancer is reassurance giving. Learning about the stochastic nature of reassurances as well as making inferential statements about the influence of covariates such as patient response and time spent on previous...

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Main Authors: Valentin Popov, Alesha Ellis-Robinson, Gerald Humphris
Format: Article
Language:English
Published: BMC 2019-01-01
Series:BMC Medical Research Methodology
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12874-018-0629-0
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author Valentin Popov
Alesha Ellis-Robinson
Gerald Humphris
author_facet Valentin Popov
Alesha Ellis-Robinson
Gerald Humphris
author_sort Valentin Popov
collection DOAJ
description Abstract Background A key element in the interaction between clinicians and patients with cancer is reassurance giving. Learning about the stochastic nature of reassurances as well as making inferential statements about the influence of covariates such as patient response and time spent on previous reassurances are of particular importance. Methods We fit Hidden Markov Models (HMMs) to reassurance type from multiple time series of clinicians’ reassurances, decoded from audio files of review consultations between patients with breast cancer and their therapeutic radiographer. Assuming a latent state process driving the observations process, HMMs naturally accommodate serial dependence in the data. Extensions to the baseline model such as including covariates as well as allowing for fixed effects for the different clinicians are straightforward to implement. Results We found that clinicians undergo different states, in which they are more or less inclined to provide a particular type of reassurance. The states are very persistent, however switches occasionally occur. The lengthier the previous reassurance, the more likely the clinician is to stay in the current state. Conclusions HMMs prove to be a valuable tool and provide important insights for practitioners. Trial registration Trial Registration number: ClinicalTrials.gov: NCT02599506. Prospectively registered on 11th March 2015.
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spelling doaj.art-eadd8757b16046ec9cb1a9b7e48d9e812022-12-22T00:02:24ZengBMCBMC Medical Research Methodology1471-22882019-01-0119111010.1186/s12874-018-0629-0Modelling reassurances of clinicians with hidden Markov modelsValentin Popov0Alesha Ellis-Robinson1Gerald Humphris2School of Mathematics and Statistics, University of St AndrewsSchool of Medicine, University of St AndrewsSchool of Medicine, University of St AndrewsAbstract Background A key element in the interaction between clinicians and patients with cancer is reassurance giving. Learning about the stochastic nature of reassurances as well as making inferential statements about the influence of covariates such as patient response and time spent on previous reassurances are of particular importance. Methods We fit Hidden Markov Models (HMMs) to reassurance type from multiple time series of clinicians’ reassurances, decoded from audio files of review consultations between patients with breast cancer and their therapeutic radiographer. Assuming a latent state process driving the observations process, HMMs naturally accommodate serial dependence in the data. Extensions to the baseline model such as including covariates as well as allowing for fixed effects for the different clinicians are straightforward to implement. Results We found that clinicians undergo different states, in which they are more or less inclined to provide a particular type of reassurance. The states are very persistent, however switches occasionally occur. The lengthier the previous reassurance, the more likely the clinician is to stay in the current state. Conclusions HMMs prove to be a valuable tool and provide important insights for practitioners. Trial registration Trial Registration number: ClinicalTrials.gov: NCT02599506. Prospectively registered on 11th March 2015.http://link.springer.com/article/10.1186/s12874-018-0629-0ReassuranceHidden Markov modelsFixed effects
spellingShingle Valentin Popov
Alesha Ellis-Robinson
Gerald Humphris
Modelling reassurances of clinicians with hidden Markov models
BMC Medical Research Methodology
Reassurance
Hidden Markov models
Fixed effects
title Modelling reassurances of clinicians with hidden Markov models
title_full Modelling reassurances of clinicians with hidden Markov models
title_fullStr Modelling reassurances of clinicians with hidden Markov models
title_full_unstemmed Modelling reassurances of clinicians with hidden Markov models
title_short Modelling reassurances of clinicians with hidden Markov models
title_sort modelling reassurances of clinicians with hidden markov models
topic Reassurance
Hidden Markov models
Fixed effects
url http://link.springer.com/article/10.1186/s12874-018-0629-0
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