Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum

The unfolded protein response (UPR) maintains cellular function under ER stress. While typically considered cell autonomous, here Lai et al. show that in Arabidopsis the UPR also has a systemic component triggered by intercellular movement of at least one bZIP transcription factor.

Bibliographic Details
Main Authors: Ya-Shiuan Lai, Giovanni Stefano, Starla Zemelis-Durfee, Cristina Ruberti, Lizzie Gibbons, Federica Brandizzi
Format: Article
Language:English
Published: Nature Portfolio 2018-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-018-06289-9
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author Ya-Shiuan Lai
Giovanni Stefano
Starla Zemelis-Durfee
Cristina Ruberti
Lizzie Gibbons
Federica Brandizzi
author_facet Ya-Shiuan Lai
Giovanni Stefano
Starla Zemelis-Durfee
Cristina Ruberti
Lizzie Gibbons
Federica Brandizzi
author_sort Ya-Shiuan Lai
collection DOAJ
description The unfolded protein response (UPR) maintains cellular function under ER stress. While typically considered cell autonomous, here Lai et al. show that in Arabidopsis the UPR also has a systemic component triggered by intercellular movement of at least one bZIP transcription factor.
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issn 2041-1723
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spelling doaj.art-eaddc50280af44e9bba846a23c30c1922022-12-21T18:03:49ZengNature PortfolioNature Communications2041-17232018-09-019111110.1038/s41467-018-06289-9Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulumYa-Shiuan Lai0Giovanni Stefano1Starla Zemelis-Durfee2Cristina Ruberti3Lizzie Gibbons4Federica Brandizzi5MSU-DOE Plant Research Lab, Michigan State UniversityMSU-DOE Plant Research Lab, Michigan State UniversityMSU-DOE Plant Research Lab, Michigan State UniversityMSU-DOE Plant Research Lab, Michigan State UniversityMSU-DOE Plant Research Lab, Michigan State UniversityMSU-DOE Plant Research Lab, Michigan State UniversityThe unfolded protein response (UPR) maintains cellular function under ER stress. While typically considered cell autonomous, here Lai et al. show that in Arabidopsis the UPR also has a systemic component triggered by intercellular movement of at least one bZIP transcription factor.https://doi.org/10.1038/s41467-018-06289-9
spellingShingle Ya-Shiuan Lai
Giovanni Stefano
Starla Zemelis-Durfee
Cristina Ruberti
Lizzie Gibbons
Federica Brandizzi
Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
Nature Communications
title Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
title_full Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
title_fullStr Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
title_full_unstemmed Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
title_short Systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
title_sort systemic signaling contributes to the unfolded protein response of the plant endoplasmic reticulum
url https://doi.org/10.1038/s41467-018-06289-9
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AT cristinaruberti systemicsignalingcontributestotheunfoldedproteinresponseoftheplantendoplasmicreticulum
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