Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management

Axial spondyloarthritis (axSpA) is a chronic inflammatory condition, with an age of onset almost exclusively under 45 years. Although symptoms are initially centred on the sacroiliac joints and spine, extraspinal manifestations are common and add considerably to the burden of disease. In this narrat...

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Main Authors: Conall MacGearailt, Gillian E. Fitzgerald
Format: Article
Language:English
Published: European Medical Journal 2021-07-01
Series:European Medical Journal Rheumatology
Subjects:
Online Access:https://www.emjreviews.com/rheumatology/article/axial-spondyloarthritis-clinical-characteristics-epidemiology-and-general-approaches-to-management-j170121/
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author Conall MacGearailt
Gillian E. Fitzgerald
author_facet Conall MacGearailt
Gillian E. Fitzgerald
author_sort Conall MacGearailt
collection DOAJ
description Axial spondyloarthritis (axSpA) is a chronic inflammatory condition, with an age of onset almost exclusively under 45 years. Although symptoms are initially centred on the sacroiliac joints and spine, extraspinal manifestations are common and add considerably to the burden of disease. In this narrative review, the authors provide an update on the epidemiology of the disease and briefly summarise the pathophysiology. The authors detail the clinical manifestations of axSpA, including an overview of axial features, peripheral manifestations, and associated comorbidities. The authors outline the current outcome measures used in the assessment of patients. Finally, the authors provide a summary of the general principles of treatment and briefly outline the role of patient education in the management of individuals with axSpA.
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spelling doaj.art-eade63f2a16d442d8d3d37d79e4ef7532022-12-21T18:49:35ZengEuropean Medical JournalEuropean Medical Journal Rheumatology2056-63952021-07-0181105114Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to ManagementConall MacGearailt0Gillian E. Fitzgerald1Department of Rheumatology, Galway University Hospital, IrelandDepartment of Rheumatology, Galway University Hospital, IrelandAxial spondyloarthritis (axSpA) is a chronic inflammatory condition, with an age of onset almost exclusively under 45 years. Although symptoms are initially centred on the sacroiliac joints and spine, extraspinal manifestations are common and add considerably to the burden of disease. In this narrative review, the authors provide an update on the epidemiology of the disease and briefly summarise the pathophysiology. The authors detail the clinical manifestations of axSpA, including an overview of axial features, peripheral manifestations, and associated comorbidities. The authors outline the current outcome measures used in the assessment of patients. Finally, the authors provide a summary of the general principles of treatment and briefly outline the role of patient education in the management of individuals with axSpA.https://www.emjreviews.com/rheumatology/article/axial-spondyloarthritis-clinical-characteristics-epidemiology-and-general-approaches-to-management-j170121/ankylosing spondylitisaxial spondyloarthritis (axspa)clinical featurespatient educationreview
spellingShingle Conall MacGearailt
Gillian E. Fitzgerald
Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management
European Medical Journal Rheumatology
ankylosing spondylitis
axial spondyloarthritis (axspa)
clinical features
patient education
review
title Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management
title_full Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management
title_fullStr Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management
title_full_unstemmed Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management
title_short Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management
title_sort axial spondyloarthritis clinical characteristics epidemiology and general approaches to management
topic ankylosing spondylitis
axial spondyloarthritis (axspa)
clinical features
patient education
review
url https://www.emjreviews.com/rheumatology/article/axial-spondyloarthritis-clinical-characteristics-epidemiology-and-general-approaches-to-management-j170121/
work_keys_str_mv AT conallmacgearailt axialspondyloarthritisclinicalcharacteristicsepidemiologyandgeneralapproachestomanagement
AT gillianefitzgerald axialspondyloarthritisclinicalcharacteristicsepidemiologyandgeneralapproachestomanagement