Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management
Axial spondyloarthritis (axSpA) is a chronic inflammatory condition, with an age of onset almost exclusively under 45 years. Although symptoms are initially centred on the sacroiliac joints and spine, extraspinal manifestations are common and add considerably to the burden of disease. In this narrat...
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Format: | Article |
Language: | English |
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European Medical Journal
2021-07-01
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Series: | European Medical Journal Rheumatology |
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Online Access: | https://www.emjreviews.com/rheumatology/article/axial-spondyloarthritis-clinical-characteristics-epidemiology-and-general-approaches-to-management-j170121/ |
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author | Conall MacGearailt Gillian E. Fitzgerald |
author_facet | Conall MacGearailt Gillian E. Fitzgerald |
author_sort | Conall MacGearailt |
collection | DOAJ |
description | Axial spondyloarthritis (axSpA) is a chronic inflammatory condition, with an age of onset almost exclusively under 45 years. Although symptoms are initially centred on the sacroiliac joints and spine, extraspinal manifestations are common and add considerably to the burden of disease. In this narrative review, the authors provide an update on the epidemiology of the disease and briefly summarise the pathophysiology. The authors detail the clinical manifestations of axSpA, including an overview of axial features, peripheral manifestations, and associated comorbidities. The authors outline the current outcome measures used in the assessment of patients. Finally, the authors provide a summary of the general principles of treatment and briefly outline the role of patient education in the management of individuals with axSpA. |
first_indexed | 2024-12-21T21:32:39Z |
format | Article |
id | doaj.art-eade63f2a16d442d8d3d37d79e4ef753 |
institution | Directory Open Access Journal |
issn | 2056-6395 |
language | English |
last_indexed | 2024-12-21T21:32:39Z |
publishDate | 2021-07-01 |
publisher | European Medical Journal |
record_format | Article |
series | European Medical Journal Rheumatology |
spelling | doaj.art-eade63f2a16d442d8d3d37d79e4ef7532022-12-21T18:49:35ZengEuropean Medical JournalEuropean Medical Journal Rheumatology2056-63952021-07-0181105114Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to ManagementConall MacGearailt0Gillian E. Fitzgerald1Department of Rheumatology, Galway University Hospital, IrelandDepartment of Rheumatology, Galway University Hospital, IrelandAxial spondyloarthritis (axSpA) is a chronic inflammatory condition, with an age of onset almost exclusively under 45 years. Although symptoms are initially centred on the sacroiliac joints and spine, extraspinal manifestations are common and add considerably to the burden of disease. In this narrative review, the authors provide an update on the epidemiology of the disease and briefly summarise the pathophysiology. The authors detail the clinical manifestations of axSpA, including an overview of axial features, peripheral manifestations, and associated comorbidities. The authors outline the current outcome measures used in the assessment of patients. Finally, the authors provide a summary of the general principles of treatment and briefly outline the role of patient education in the management of individuals with axSpA.https://www.emjreviews.com/rheumatology/article/axial-spondyloarthritis-clinical-characteristics-epidemiology-and-general-approaches-to-management-j170121/ankylosing spondylitisaxial spondyloarthritis (axspa)clinical featurespatient educationreview |
spellingShingle | Conall MacGearailt Gillian E. Fitzgerald Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management European Medical Journal Rheumatology ankylosing spondylitis axial spondyloarthritis (axspa) clinical features patient education review |
title | Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management |
title_full | Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management |
title_fullStr | Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management |
title_full_unstemmed | Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management |
title_short | Axial Spondyloarthritis: Clinical Characteristics, Epidemiology, and General Approaches to Management |
title_sort | axial spondyloarthritis clinical characteristics epidemiology and general approaches to management |
topic | ankylosing spondylitis axial spondyloarthritis (axspa) clinical features patient education review |
url | https://www.emjreviews.com/rheumatology/article/axial-spondyloarthritis-clinical-characteristics-epidemiology-and-general-approaches-to-management-j170121/ |
work_keys_str_mv | AT conallmacgearailt axialspondyloarthritisclinicalcharacteristicsepidemiologyandgeneralapproachestomanagement AT gillianefitzgerald axialspondyloarthritisclinicalcharacteristicsepidemiologyandgeneralapproachestomanagement |