Association of BACE1 Gene Polymorphism with Cerebellar Volume but Not Cognitive Function in Normal Individuals

Association of BACE1 Gene Polymorphism with Cerebellar Volume but Not Cognitive Function in Normal Individuals

Aims: β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1) is a biological and positional candidate gene for Alzheimer’s disease (AD). Previous studies found that BACE1-null mice had impaired performance on cognition and neurodegeneration during the aging process. Additionally, a synonym...

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Bibliographic Details
Main Authors: Alex Tsai, Chu-Chung Huang, Albert C. Yang, Mu-En Liu, Pei-Chi Tu, Chen-Jee Hong, Ying-Jay Liou, Jin-Fan Chen, Ching-Po Lin, Shih-Jen Tsai
Format: Article
Language:English
Published: Karger Publishers 2012-12-01
Series:Dementia and Geriatric Cognitive Disorders Extra
Subjects:
β-Site amyloid precursor protein-cleaving enzyme 1
Volumetry
Cognition
Polymorphism
Cerebellum
Online Access:http://www.karger.com/Article/FullText/345980

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