Amyloid proteins and their role in multiple sclerosis. Considerations in the use of amyloid-PET imaging

Amyloid proteins and their role in multiple sclerosis. Considerations in the use of amyloid-PET imaging

Thioflavin T derivatives are used in positron-emission tomography (PET) studies to detect amyloid protein deposits in patients with Alzheimer disease. These tracers bind extensively to white matter, which suggests that they may be useful in studies of multiple sclerosis (MS), and that proteins resul...

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Bibliographic Details
Main Authors: Jordi A. eMatias-Guiu, Celia eOreja-Guevara, Maria Nieves eCabrera-Martin, Teresa eMoreno-Ramos, José Luis eCarreras, Jorge eMatias-Guiu
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-03-01
Series:Frontiers in Neurology
Subjects:
Amyloid
Multiple Sclerosis
biomarkers
amyloid precursor protein
white matter
positron emission tomography
Online Access:http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00053/full

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