Bioprinting microporous functional living materials from protein-based core-shell microgels

Extrusion bioprinting can be used to produce living materials but controlling cell microenvironments is challenging. Here, the authors use a type of core-shell microgel ink that decouples cell culture from material processing to produce functional materials with a range of potential applications.

Bibliographic Details
Main Authors: Yangteng Ou, Shixiang Cao, Yang Zhang, Hongjia Zhu, Chengzhi Guo, Wei Yan, Fengxue Xin, Weiliang Dong, Yanli Zhang, Masashi Narita, Ziyi Yu, Tuomas P. J. Knowles
Format: Article
Language:English
Published: Nature Portfolio 2023-01-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-35140-5
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author Yangteng Ou
Shixiang Cao
Yang Zhang
Hongjia Zhu
Chengzhi Guo
Wei Yan
Fengxue Xin
Weiliang Dong
Yanli Zhang
Masashi Narita
Ziyi Yu
Tuomas P. J. Knowles
author_facet Yangteng Ou
Shixiang Cao
Yang Zhang
Hongjia Zhu
Chengzhi Guo
Wei Yan
Fengxue Xin
Weiliang Dong
Yanli Zhang
Masashi Narita
Ziyi Yu
Tuomas P. J. Knowles
author_sort Yangteng Ou
collection DOAJ
description Extrusion bioprinting can be used to produce living materials but controlling cell microenvironments is challenging. Here, the authors use a type of core-shell microgel ink that decouples cell culture from material processing to produce functional materials with a range of potential applications.
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spelling doaj.art-eae3b608e61844ff99a5cf08e6f009322023-01-22T12:19:38ZengNature PortfolioNature Communications2041-17232023-01-0114111410.1038/s41467-022-35140-5Bioprinting microporous functional living materials from protein-based core-shell microgelsYangteng Ou0Shixiang Cao1Yang Zhang2Hongjia Zhu3Chengzhi Guo4Wei Yan5Fengxue Xin6Weiliang Dong7Yanli Zhang8Masashi Narita9Ziyi Yu10Tuomas P. J. Knowles11State Key Laboratory of Materials-oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech UniversityState Key Laboratory of Materials-oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech UniversityState Key Laboratory of Materials-oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech UniversityYusuf Hamied Department of Chemistry, University of CambridgeState Key Laboratory of Materials-oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech UniversityState Key Laboratory of Materials-oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech UniversityState Key Laboratory of Materials-oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech UniversityState Key Laboratory of Materials-oriented Chemical Engineering, College of Biotechnology and Pharmaceutical Engineering, Nanjing Tech UniversityYusuf Hamied Department of Chemistry, University of CambridgeCancer Research UK Cambridge Institute, University of CambridgeState Key Laboratory of Materials-oriented Chemical Engineering, College of Chemical Engineering, Nanjing Tech UniversityYusuf Hamied Department of Chemistry, University of CambridgeExtrusion bioprinting can be used to produce living materials but controlling cell microenvironments is challenging. Here, the authors use a type of core-shell microgel ink that decouples cell culture from material processing to produce functional materials with a range of potential applications.https://doi.org/10.1038/s41467-022-35140-5
spellingShingle Yangteng Ou
Shixiang Cao
Yang Zhang
Hongjia Zhu
Chengzhi Guo
Wei Yan
Fengxue Xin
Weiliang Dong
Yanli Zhang
Masashi Narita
Ziyi Yu
Tuomas P. J. Knowles
Bioprinting microporous functional living materials from protein-based core-shell microgels
Nature Communications
title Bioprinting microporous functional living materials from protein-based core-shell microgels
title_full Bioprinting microporous functional living materials from protein-based core-shell microgels
title_fullStr Bioprinting microporous functional living materials from protein-based core-shell microgels
title_full_unstemmed Bioprinting microporous functional living materials from protein-based core-shell microgels
title_short Bioprinting microporous functional living materials from protein-based core-shell microgels
title_sort bioprinting microporous functional living materials from protein based core shell microgels
url https://doi.org/10.1038/s41467-022-35140-5
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