Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia

BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vita...

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Main Authors: M Alvandipour, P Tayebi, R Alizadeh Navaie, H Khodabakhshi
Format: Article
Language:English
Published: Babol University of Medical Sciences 2011-03-01
Series:Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
Subjects:
Online Access:http://jbums.org/article-1-3734-en.html
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author M Alvandipour
P Tayebi
R Alizadeh Navaie
H Khodabakhshi
author_facet M Alvandipour
P Tayebi
R Alizadeh Navaie
H Khodabakhshi
author_sort M Alvandipour
collection DOAJ
description BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vitamin E in treatment of cyclic mastalgia and to find the best treatment for it. METHODS: This study was done as a double blind clinical trial on 100 women suffered cyclic mastalgia. Patients was divided in 4 study groups with 25 patients in each group, included: 1. Evening Primrose oil 2 gr/day, 2. Vitamin E 400 unit daily, 3. Evening Primrose oil and Vitamin E, 4. Placebo. The MC Gill Questionnaires was used for patients pain evaluation before study and 1 and 6 months after intervention.FINDINGS: The mean of MC Gill score in Primrose oil group before investigation was 6.23±1.004 and was decreased to 2.68±1.002 six months after primrose oil consumption. Also in Vitamin E group this mount was decreased from 6.04±1.342 to 3.06±1.482. Overally the mean of MC Gill score in each of three therapeutic group was decreased after the intervention against placebo group (p=0.000). Also the difference of MC Gill score between these three therapeutic groups hasn any significant change. CONCLUSION: The results of present study show that Vitamin E and Primrose oil have a same therapeutic effect in the treatment of cyclic mastalgia and these drugs can be used as a suitable therapeutic alternative in the patient with cyclic mastalgia.
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spelling doaj.art-eaeb2eea7aa94ef4a3683ecda4bb02982022-12-21T20:44:37ZengBabol University of Medical SciencesMajallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul1561-41072251-71702011-03-01132711Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic MastalgiaM Alvandipour0P Tayebi1R Alizadeh Navaie2H Khodabakhshi3 BACKGROUND AND OBJECTIVE: Mastalgia is a common painful complaint in women. Several different therapeutic components are used for mastalgia treatment. Vitamin E and Evening Primrose oil (EPO) are some of these components that used for cyclic mastalgia. This study was designed to compare EPO and Vitamin E in treatment of cyclic mastalgia and to find the best treatment for it. METHODS: This study was done as a double blind clinical trial on 100 women suffered cyclic mastalgia. Patients was divided in 4 study groups with 25 patients in each group, included: 1. Evening Primrose oil 2 gr/day, 2. Vitamin E 400 unit daily, 3. Evening Primrose oil and Vitamin E, 4. Placebo. The MC Gill Questionnaires was used for patients pain evaluation before study and 1 and 6 months after intervention.FINDINGS: The mean of MC Gill score in Primrose oil group before investigation was 6.23±1.004 and was decreased to 2.68±1.002 six months after primrose oil consumption. Also in Vitamin E group this mount was decreased from 6.04±1.342 to 3.06±1.482. Overally the mean of MC Gill score in each of three therapeutic group was decreased after the intervention against placebo group (p=0.000). Also the difference of MC Gill score between these three therapeutic groups hasn any significant change. CONCLUSION: The results of present study show that Vitamin E and Primrose oil have a same therapeutic effect in the treatment of cyclic mastalgia and these drugs can be used as a suitable therapeutic alternative in the patient with cyclic mastalgia.http://jbums.org/article-1-3734-en.htmlcyclic mastalgiavitamin eprimrose oil
spellingShingle M Alvandipour
P Tayebi
R Alizadeh Navaie
H Khodabakhshi
Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul
cyclic mastalgia
vitamin e
primrose oil
title Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_full Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_fullStr Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_full_unstemmed Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_short Comparison between Effect of Evening Primrose Oil and Vitamin E in Treatment of Cyclic Mastalgia
title_sort comparison between effect of evening primrose oil and vitamin e in treatment of cyclic mastalgia
topic cyclic mastalgia
vitamin e
primrose oil
url http://jbums.org/article-1-3734-en.html
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AT ptayebi comparisonbetweeneffectofeveningprimroseoilandvitamineintreatmentofcyclicmastalgia
AT ralizadehnavaie comparisonbetweeneffectofeveningprimroseoilandvitamineintreatmentofcyclicmastalgia
AT hkhodabakhshi comparisonbetweeneffectofeveningprimroseoilandvitamineintreatmentofcyclicmastalgia