Brief Histories of Retroviral Integration Research and Associated International Conferences

Brief Histories of Retroviral Integration Research and Associated International Conferences

The field of retroviral integration research has a long history that started with the provirus hypothesis and subsequent discoveries of the retroviral reverse transcriptase and integrase enzymes. Because both enzymes are essential for retroviral replication, they became valued targets in the effort...

Bibliografski detalji
Glavni autori:	Duane P. Grandgenett, Alan N. Engelman
Format:	Članak
Jezik:	English
Izdano:	MDPI AG 2024-04-01
Serija:	Viruses
Teme:	integrase retroviral integration provirus integrase strand transfer inhibitor raltegravir elvitegravir
Online pristup:	https://www.mdpi.com/1999-4915/16/4/604

Slični predmeti

Multiple choices for HIV therapy with integrase strand transfer inhibitors
od: Raffi Francois, i dr.
Izdano: (2012-12-01)

Effectiveness and safety of integrase strand transfer inhibitors in Spain: a prospective real-world study
od: José Ramón Santos, i dr.
Izdano: (2023-06-01)

HIV/HCV-coinfection: which role can new antiretrovirals such as integrase inhibitors play?
od: Vogel Martin, i dr.
Izdano: (2009-11-01)

Inhibition of HTLV-1 Infection by HIV-1 First- and Second-Generation Integrase Strand Transfer Inhibitors
od: Michał S. Barski, i dr.
Izdano: (2019-08-01)

Resistance to inhibitors of the human immunodeficiency virus type 1 integration
od: Daria J Hazuda

Durability of switch regimens based on rilpivirine or on integrase inhibitors, both in association with tenofovir and emtricitabine, in HIV-infected, virologically suppressed patients
od: Nicola Gianotti, i dr.
Izdano: (2017-11-01)

A clinical review of HIV integrase strand transfer inhibitors (INSTIs) for the prevention and treatment of HIV-1 infection
od: Alexa Vyain Zhao, i dr.
Izdano: (2022-10-01)

From protease inhibitors to integrase strand transfer inhibitors: the evolution of HIV drug resistance management
od: HU Zhiliang, YANG Yongfeng
Izdano: (2025-01-01)

Resistance against Integrase Strand Transfer Inhibitors and Relevance to HIV Persistence
od: Thibault Mesplède, i dr.
Izdano: (2015-07-01)

Resistance to Integrase Inhibitors
od: Mathieu Métifiot, i dr.
Izdano: (2010-06-01)

HIV-1 resistance patterns to integrase inhibitors in Chilean patients with virological failure on raltegravir-containing regimens
od: Pablo Ferrer, i dr.
Izdano: (2020-09-01)

HIV INTEGRASE INHIBITORS: THE BASIS OF EFFECTIVE AND SAFE ANTIRETROVIRAL THERAPY
od: V. I. SHAKHGILDYAN
Izdano: (2017-05-01)

Modern antiretroviral regimens
od: A. V. Kravchenko
Izdano: (2016-12-01)

G140S/Q148R and N155H mutations render HIV-2 Integrase resistant to Raltegravir whereas Y143C does not
od: Damond Florence, i dr.
Izdano: (2011-08-01)

Raltegravir is the first HIV integrase inhibitor as part of antiretroviral treatment regimens
od: Aleksey Viktorovich Kravchenko, i dr.
Izdano: (2010-11-01)

Integrase inhibitors versus efavirenz combination antiretroviral therapies for TB/HIV coinfection: a meta-analysis of randomized controlled trials
od: Yuanlu Shu, i dr.
Izdano: (2021-05-01)

Are new antiretroviral treatments increasing the risks of clinical obesity?
od: Andrew Hill, i dr.
Izdano: (2019-01-01)

Dolutegravir-based anti-retroviral therapy is effective and safe in HIV–infected paediatric patients
od: Eugenia Bruzzese, i dr.
Izdano: (2018-03-01)

R263K Mutation Leading to Failure of Dolutegravir-Based Treatment in a HIV Patient also Receiving Rifampicin: A Case Report
od: Jin Li, i dr.
Izdano: (2023-05-01)

Multimodal Functionalities of HIV-1 Integrase
od: Alan N. Engelman, i dr.
Izdano: (2022-04-01)

Retroviral integration: A critical step in viral life cycle suitable for drug intervention
od: Celia Fernández-Ortega, i dr.
Izdano: (2011-12-01)

Cerebral function parameters in people with HIV switching integrase inhibitors: a randomized controlled trial
od: Borja Mora-Peris, i dr.
Izdano: (2021-12-01)

HIV-1 acquired drug resistance to integrase inhibitors in a cohort of antiretroviral therapy multi-experienced Mexican patients failing to raltegravir: a cross-sectional study
od: Aurelio Orta-Resendiz, i dr.
Izdano: (2020-02-01)

Raltegravir-Induced Adaptations of the HIV-1 Integrase: Analysis of Structure, Variability, and Mutation Co-occurrence
od: Lucas de Almeida Machado, i dr.
Izdano: (2019-09-01)

Raltegravir: molecular basis of its mechanism of action
od: Mouscadet Jean-François, i dr.
Izdano: (2009-11-01)

Profile of bictegravir/emtricitabine/tenofovir alafenamide fixed dose combination and its potential in the treatment of HIV-1 infection: evidence to date
od: Hill L, i dr.
Izdano: (2018-10-01)

Different Pathways Conferring Integrase Strand-Transfer Inhibitors Resistance
od: Clémence Richetta, i dr.
Izdano: (2022-11-01)

Efficacy of Integrase Strand Transfer Inhibitors and the Capsid Inhibitor Lenacapavir against HIV-2, and Exploring the Effect of Raltegravir on the Activity of SARS-CoV-2
od: Irene Wanjiru Kiarie, i dr.
Izdano: (2024-10-01)

Modulation of chromatin structure by the FACT histone chaperone complex regulates HIV-1 integration
od: Julien Matysiak, i dr.
Izdano: (2017-07-01)

HIV-1 integrase resistance among antiretroviral treatment naive and experienced patients from Northwestern Poland
od: Parczewski Miłosz, i dr.
Izdano: (2012-12-01)

Quantitative prediction of integrase inhibitor resistance from genotype through consensus linear regression modeling
od: Van der Borght Koen, i dr.
Izdano: (2013-01-01)

Structural Insights on Retroviral DNA Integration: Learning from Foamy Viruses
od: Ga-Eun Lee, i dr.
Izdano: (2019-08-01)

Risk of Cardiovascular Events in People with HIV (PWH) Treated with Integrase Strand-Transfer Inhibitors: The Debate Is Not Over; Results of the SCOLTA Study
od: Nicolò Corti, i dr.
Izdano: (2024-04-01)

Weight gain on dolutegravir: Association is not the same as causation
od: Gary Maartens, i dr.
Izdano: (2023-05-01)

Pharmacokinetic drug interactions of integrase strand transfer inhibitors
od: Chi-Hua Lu, i dr.
Izdano: (2021-01-01)

Clinical Outcomes of Integrase Strand Transfer Inhibitors Containing Antiretroviral Therapy in HIV-2: A Narrative Review
od: Wendy J. Boschloo, i dr.
Izdano: (2024-05-01)

HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Integration
od: Min Li, i dr.
Izdano: (2024-07-01)

Novel therapeutic strategies targeting HIV integrase
od: Quashie Peter K, i dr.
Izdano: (2012-04-01)

Allosteric Integrase Inhibitor Influences on HIV-1 Integration and Roles of LEDGF/p75 and HDGFL2 Host Factors
od: Parmit Kumar Singh, i dr.
Izdano: (2022-08-01)

Modulation of the functional association between the HIV-1 intasome and the nucleosome by histone amino-terminal tails
od: Mohamed S. Benleulmi, i dr.
Izdano: (2017-11-01)