The size of the EB cap determines instantaneous microtubule stability

The size of the EB cap determines instantaneous microtubule stability

The function of microtubules relies on their ability to switch between phases of growth and shrinkage. A nucleotide-dependent stabilising cap at microtubule ends is thought to be lost before this switch can occur; however, the nature and size of this protective cap are unknown. Using a microfluidics...

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Bibliographic Details
Main Authors: Christian Duellberg, Nicholas I Cade, David Holmes, Thomas Surrey
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2016-04-01
Series:eLife
Subjects:
TIRF microscopy
EB proteins
microtubule dynamic instability
end tracking
in vitro reconstitution
microfluids
Online Access:https://elifesciences.org/articles/13470

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