Bevacizumab attenuates hepatic fibrosis in rats by inhibiting activation of hepatic stellate cells.
Angiogenesis is a fundamental part of the response to tissue injury, which is involved in the development of hepatic fibrosis. Vascular endothelial growth factor plays an important role in angiogenesis. The expression of VEGF is increased during hepatic fibrogenesis and correlates with the micro-ves...
Main Authors: | Yangqing Huang, Helin Feng, Tong Kan, Bin Huang, Minfeng Zhang, Yesheng Li, Changying Shi, Mengchao Wu, Yunquan Luo, Jiamei Yang, Feng Xu |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3758295?pdf=render |
Similar Items
-
Novel matrine derivative MD-1 attenuates hepatic fibrosis by inhibiting EGFR activation of hepatic stellate cells
by: Yi Feng, et al.
Published: (2016-06-01) -
RANKL inhibits activation of hepatic stellate cells during hepatic fibrosis in mice
by: ZHOU Lijia, et al.
Published: (2023-01-01) -
Fibronectin Type III Domain-Containing 5 Attenuates Liver Fibrosis Via Inhibition of Hepatic Stellate Cell Activation
by: Bing Zhou, et al.
Published: (2018-07-01) -
JCAD deficiency attenuates activation of hepatic stellate cells and cholestatic fibrosis
by: Li Xie, et al.
Published: (2024-04-01) -
The Dual-Mode Transition of Myofibroblasts Derived from Hepatic Stellate Cells in Liver Fibrosis
by: Mengchao Yan, et al.
Published: (2023-10-01)