Intranasal Vaccination With Lipoproteins Confers Protection Against Pneumococcal Colonisation

Intranasal Vaccination With Lipoproteins Confers Protection Against Pneumococcal Colonisation

Streptococcus pneumoniae is endowed with a variety of surface-exposed proteins representing putative vaccine candidates. Lipoproteins are covalently anchored to the cell membrane and highly conserved among pneumococcal serotypes. Here, we evaluated these lipoproteins for their immunogenicity and pro...

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Bibliographic Details
Main Authors: Franziska Voß, Thomas P. Kohler, Tanja Meyer, Mohammed R. Abdullah, Fred J. van Opzeeland, Malek Saleh, Stephan Michalik, Saskia van Selm, Frank Schmidt, Marien I. de Jonge, Sven Hammerschmidt
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
Streptococcus pneumoniae
lipoprotein
immunogenicity
colonization
protection
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02405/full

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