A method for generation phage cocktail with great therapeutic potential.
BACKGROUND: Bacteriophage could be an alternative to conventional antibiotic therapy against multidrug-resistant bacteria. However, the emergence of resistant variants after phage treatment limited its therapeutic application. METHODOLOGY/PRINCIPAL FINDINGS: In this study, an approach, named "S...
Main Authors: | Jingmin Gu, Xiaohe Liu, Yue Li, Wenyu Han, Liancheng Lei, Yongjun Yang, Honglei Zhao, Yu Gao, Jun Song, Rong Lu, Changjiang Sun, Xin Feng |
---|---|
Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2012-01-01
|
Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3291564?pdf=render |
Similar Items
-
The Combination of Phages and Faecal Microbiota Transplantation Can Effectively Treat Mouse Colitis Caused by Salmonella enterica Serovar Typhimurium
by: Xinwu Wang, et al.
Published: (2022-07-01) -
Computational Basis for On-Demand Production of Diversified Therapeutic Phage Cocktails
by: Catherine M. Mageeney, et al.
Published: (2020-08-01) -
RETRACTED: vB-ApyS-JF1, the First Trueperella pyogenes Phage, Shows Potential as an Alternative Treatment Strategy for Trueperella pyogenes Infections
by: Yalu Ji, et al.
Published: (2021-10-01) -
Metagenomic Analysis of Therapeutic PYO Phage Cocktails from 1997 to 2014
by: Julia Villarroel, et al.
Published: (2017-11-01) -
Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin.
by: Jingmin Gu, et al.
Published: (2014-05-01)