Jailed Balloon Technique Is Superior to Jailed Wire Technique in Reducing the Rate of Side Branch Occlusion: Subgroup Analysis of the Conventional Versus Intentional StraTegy in Patients With High Risk PrEdiction of Side Branch OccLusion in Coronary Bifurcation InterVEntion Trial
ObjectiveJailed balloon technique (JBT) is an active side branch (SB) protection strategy and is considered to be superior to the jailed wire technique (JWT) in reducing SB occlusion. However, no randomized trials have proved that. We aim to investigate whether JBT could decrease the SB occlusion ra...
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| Format: | Article |
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Frontiers Media S.A.
2022-03-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2022.814873/full |
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| author | Dong Zhang Dong Zhang Dong Zhang Zhiyong Zhao Zhiyong Zhao Zhiyong Zhao Guofeng Gao Guofeng Gao Guofeng Gao Han Xu Han Xu Han Xu Hao Wang Hao Wang Hao Wang Shuai Liu Shuai Liu Shuai Liu Dong Yin Dong Yin Dong Yin Lei Feng Lei Feng Lei Feng Chenggang Zhu Chenggang Zhu Chenggang Zhu Yang Wang Yanyan Zhao Yuejin Yang Yuejin Yang Yuejin Yang Runlin Gao Runlin Gao Runlin Gao Bo Xu Bo Xu Bo Xu Kefei Dou Kefei Dou Kefei Dou |
| author_facet | Dong Zhang Dong Zhang Dong Zhang Zhiyong Zhao Zhiyong Zhao Zhiyong Zhao Guofeng Gao Guofeng Gao Guofeng Gao Han Xu Han Xu Han Xu Hao Wang Hao Wang Hao Wang Shuai Liu Shuai Liu Shuai Liu Dong Yin Dong Yin Dong Yin Lei Feng Lei Feng Lei Feng Chenggang Zhu Chenggang Zhu Chenggang Zhu Yang Wang Yanyan Zhao Yuejin Yang Yuejin Yang Yuejin Yang Runlin Gao Runlin Gao Runlin Gao Bo Xu Bo Xu Bo Xu Kefei Dou Kefei Dou Kefei Dou |
| author_sort | Dong Zhang |
| collection | DOAJ |
| description | ObjectiveJailed balloon technique (JBT) is an active side branch (SB) protection strategy and is considered to be superior to the jailed wire technique (JWT) in reducing SB occlusion. However, no randomized trials have proved that. We aim to investigate whether JBT could decrease the SB occlusion rate.MethodsConventional versus Intentional straTegy in patients with high Risk prEdiction of Side branch OccLusion in coronary bifurcation interVEntion (CIT-RESOLVE) (NCT02644434, registered on December 31, 2015) (https://clinicaltrials.gov) is a randomized trial that assessed the effects of different strategies on SB occlusion rate in patients with a high risk of SB occlusion. The present subgroup analysis enrolled bifurcation lesions (2 mm ≤ reference vessel diameter of SB < 2.5 mm) with Visual estimation for Risk prEdiction of Side branch OccLusion in coronary bifurcation intervention (V-RESOLVE) score ≥ 12 points. The primary endpoint is SB occlusion. One-year clinical events were compared.ResultsA total of 284 subjects at 16 sites were randomly assigned to the JBT group (n = 143) or the JWT group (n = 141). The rate of SB occlusion (9.1 vs. 19.9%, p = 0.02) and periprocedural myocardial infarction (defined by WHO, 7 vs. 14.9%, p = 0.03) is significantly lower in the JBT group than in the JWT group. The JBT and JWT groups showed no significant differences in cardiac death (0.7 vs. 0.7%, p = 1), myocardial infarction (MI, 6.3 vs. 7.1%, p = 0.79), target lesion revascularization (TLR, 1.4 vs. 2.1%, p = 0.68), and major cardiac adverse events (MACE, a composite of all-cause death, MI, or TLR, 8.4 vs. 10.6%, p = 0.52) during a 1-year follow-up.ConclusionIn patients with a high risk of SB occlusion (V-RESOLVE score ≥ 12 points), JBT is superior to JWT in reducing SB occlusion. However, no significant differences were detected in 1-year MACE. |
| first_indexed | 2024-12-22T16:42:05Z |
| format | Article |
| id | doaj.art-eaf8c6792c8b40f1a89d7ad4f09bdcb1 |
| institution | Directory Open Access Journal |
| issn | 2297-055X |
| language | English |
| last_indexed | 2024-12-22T16:42:05Z |
| publishDate | 2022-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj.art-eaf8c6792c8b40f1a89d7ad4f09bdcb12022-12-21T18:19:50ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2022-03-01910.3389/fcvm.2022.814873814873Jailed Balloon Technique Is Superior to Jailed Wire Technique in Reducing the Rate of Side Branch Occlusion: Subgroup Analysis of the Conventional Versus Intentional StraTegy in Patients With High Risk PrEdiction of Side Branch OccLusion in Coronary Bifurcation InterVEntion TrialDong Zhang0Dong Zhang1Dong Zhang2Zhiyong Zhao3Zhiyong Zhao4Zhiyong Zhao5Guofeng Gao6Guofeng Gao7Guofeng Gao8Han Xu9Han Xu10Han Xu11Hao Wang12Hao Wang13Hao Wang14Shuai Liu15Shuai Liu16Shuai Liu17Dong Yin18Dong Yin19Dong Yin20Lei Feng21Lei Feng22Lei Feng23Chenggang Zhu24Chenggang Zhu25Chenggang Zhu26Yang Wang27Yanyan Zhao28Yuejin Yang29Yuejin Yang30Yuejin Yang31Runlin Gao32Runlin Gao33Runlin Gao34Bo Xu35Bo Xu36Bo Xu37Kefei Dou38Kefei Dou39Kefei Dou40State Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaMedical Research and Biometrics Center, National Center for Cardiovascular Diseases, Beijing, ChinaMedical Research and Biometrics Center, National Center for Cardiovascular Diseases, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaCatheterization Laboratories, Fu Wai Hospital, Beijing, ChinaState Key Laboratory of Cardiovascular Disease, Beijing, ChinaDepartment of Cardiology, National Center for Cardiovascular Diseases, Fu Wai Hospital, Beijing, ChinaChinese Academy of Medical Sciences and Peking Union Medical College, Beijing, ChinaObjectiveJailed balloon technique (JBT) is an active side branch (SB) protection strategy and is considered to be superior to the jailed wire technique (JWT) in reducing SB occlusion. However, no randomized trials have proved that. We aim to investigate whether JBT could decrease the SB occlusion rate.MethodsConventional versus Intentional straTegy in patients with high Risk prEdiction of Side branch OccLusion in coronary bifurcation interVEntion (CIT-RESOLVE) (NCT02644434, registered on December 31, 2015) (https://clinicaltrials.gov) is a randomized trial that assessed the effects of different strategies on SB occlusion rate in patients with a high risk of SB occlusion. The present subgroup analysis enrolled bifurcation lesions (2 mm ≤ reference vessel diameter of SB < 2.5 mm) with Visual estimation for Risk prEdiction of Side branch OccLusion in coronary bifurcation intervention (V-RESOLVE) score ≥ 12 points. The primary endpoint is SB occlusion. One-year clinical events were compared.ResultsA total of 284 subjects at 16 sites were randomly assigned to the JBT group (n = 143) or the JWT group (n = 141). The rate of SB occlusion (9.1 vs. 19.9%, p = 0.02) and periprocedural myocardial infarction (defined by WHO, 7 vs. 14.9%, p = 0.03) is significantly lower in the JBT group than in the JWT group. The JBT and JWT groups showed no significant differences in cardiac death (0.7 vs. 0.7%, p = 1), myocardial infarction (MI, 6.3 vs. 7.1%, p = 0.79), target lesion revascularization (TLR, 1.4 vs. 2.1%, p = 0.68), and major cardiac adverse events (MACE, a composite of all-cause death, MI, or TLR, 8.4 vs. 10.6%, p = 0.52) during a 1-year follow-up.ConclusionIn patients with a high risk of SB occlusion (V-RESOLVE score ≥ 12 points), JBT is superior to JWT in reducing SB occlusion. However, no significant differences were detected in 1-year MACE.https://www.frontiersin.org/articles/10.3389/fcvm.2022.814873/fullcoronary bifurcation lesionsjailed balloon techniquejailed wire techniqueside branch occlusionmajor adverse cardiac event (MACE) |
| spellingShingle | Dong Zhang Dong Zhang Dong Zhang Zhiyong Zhao Zhiyong Zhao Zhiyong Zhao Guofeng Gao Guofeng Gao Guofeng Gao Han Xu Han Xu Han Xu Hao Wang Hao Wang Hao Wang Shuai Liu Shuai Liu Shuai Liu Dong Yin Dong Yin Dong Yin Lei Feng Lei Feng Lei Feng Chenggang Zhu Chenggang Zhu Chenggang Zhu Yang Wang Yanyan Zhao Yuejin Yang Yuejin Yang Yuejin Yang Runlin Gao Runlin Gao Runlin Gao Bo Xu Bo Xu Bo Xu Kefei Dou Kefei Dou Kefei Dou Jailed Balloon Technique Is Superior to Jailed Wire Technique in Reducing the Rate of Side Branch Occlusion: Subgroup Analysis of the Conventional Versus Intentional StraTegy in Patients With High Risk PrEdiction of Side Branch OccLusion in Coronary Bifurcation InterVEntion Trial Frontiers in Cardiovascular Medicine coronary bifurcation lesions jailed balloon technique jailed wire technique side branch occlusion major adverse cardiac event (MACE) |
| title | Jailed Balloon Technique Is Superior to Jailed Wire Technique in Reducing the Rate of Side Branch Occlusion: Subgroup Analysis of the Conventional Versus Intentional StraTegy in Patients With High Risk PrEdiction of Side Branch OccLusion in Coronary Bifurcation InterVEntion Trial |
| title_full | Jailed Balloon Technique Is Superior to Jailed Wire Technique in Reducing the Rate of Side Branch Occlusion: Subgroup Analysis of the Conventional Versus Intentional StraTegy in Patients With High Risk PrEdiction of Side Branch OccLusion in Coronary Bifurcation InterVEntion Trial |
| title_fullStr | Jailed Balloon Technique Is Superior to Jailed Wire Technique in Reducing the Rate of Side Branch Occlusion: Subgroup Analysis of the Conventional Versus Intentional StraTegy in Patients With High Risk PrEdiction of Side Branch OccLusion in Coronary Bifurcation InterVEntion Trial |
| title_full_unstemmed | Jailed Balloon Technique Is Superior to Jailed Wire Technique in Reducing the Rate of Side Branch Occlusion: Subgroup Analysis of the Conventional Versus Intentional StraTegy in Patients With High Risk PrEdiction of Side Branch OccLusion in Coronary Bifurcation InterVEntion Trial |
| title_short | Jailed Balloon Technique Is Superior to Jailed Wire Technique in Reducing the Rate of Side Branch Occlusion: Subgroup Analysis of the Conventional Versus Intentional StraTegy in Patients With High Risk PrEdiction of Side Branch OccLusion in Coronary Bifurcation InterVEntion Trial |
| title_sort | jailed balloon technique is superior to jailed wire technique in reducing the rate of side branch occlusion subgroup analysis of the conventional versus intentional strategy in patients with high risk prediction of side branch occlusion in coronary bifurcation intervention trial |
| topic | coronary bifurcation lesions jailed balloon technique jailed wire technique side branch occlusion major adverse cardiac event (MACE) |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2022.814873/full |
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