Correlation between the pressure-to-cornea index and both structural and functional measures of glaucoma

Purpose: the pressure-to-cornea index (PCI) was proposed in order to integrate intraocular pressure and central cornea thickness as a single-risk factor for glaucoma. The purpose of this study was to correlate the PCI with a structural and two functional measures of glaucoma. Setting: University Hos...

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Bibliographic Details
Main Authors: Andrea MBV Franco, Niro Kasahara
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2014-01-01
Series:Indian Journal of Ophthalmology
Subjects:
Online Access:http://www.ijo.in/article.asp?issn=0301-4738;year=2014;volume=62;issue=9;spage=907;epage=910;aulast=Franco
Description
Summary:Purpose: the pressure-to-cornea index (PCI) was proposed in order to integrate intraocular pressure and central cornea thickness as a single-risk factor for glaucoma. The purpose of this study was to correlate the PCI with a structural and two functional measures of glaucoma. Setting: University Hospital in South America. Materials and Methods: Pressure-to-cornea index was calculated for 70 eyes of 36 subjects (glaucoma and suspects). Cup-to-disc (C/D) ratio, mean deviation (MD) and pattern standard deviation (PSD) as recorded by Humphrey automated perimetry (SITA 24-2) were correlated with PCI (Pearson′s correlation coefficient). Results: Pearson′s correlation coefficient between PCI and C/D was 0.329 (95% confidence interval [95% CI], 0.09-0.526; P = 0.006); between PCI and MD was − 0.356 MD (95% CI, −0.549 to − 0.126; P = 0.003); and between PCI and PSD was − 0.215 (95% CI, −0.433 to 0.025; P = 0.07). Conclusion: In addition to serve as a single-risk factor, PCI can be used to stage glaucoma severity as well.
ISSN:0301-4738
1998-3689