Vitamin D level among patients with unexplained musculoskeletal symptoms
Background: Unexplained musculoskeletal (MSK) symptoms sometimes pose diagnostic and management challenges and can lead to prolonged suffering and disability. Hypovitaminosis D could be a reason for such symptoms. This study aimed to determine the vitamin D level among patients with unexplained MSK...
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Bangabandhu Sheikh Mujib Medical University
2023-12-01
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| Series: | Bangabandhu Sheikh Mujib Medical University Journal |
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| Online Access: | https://www.banglajol.info/index.php/BSMMUJ/article/view/70186 |
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| author | Md. Abdur Razzaque Iftekhar Hussain Bandhan Rijwan Bhuiyan Mohammad Ziaul Haider Mirza Nurul Karim Minhaj Rahim Choudhury |
| author_facet | Md. Abdur Razzaque Iftekhar Hussain Bandhan Rijwan Bhuiyan Mohammad Ziaul Haider Mirza Nurul Karim Minhaj Rahim Choudhury |
| author_sort | Md. Abdur Razzaque |
| collection | DOAJ |
| description |
Background: Unexplained musculoskeletal (MSK) symptoms sometimes pose diagnostic and management challenges and can lead to prolonged suffering and disability. Hypovitaminosis D could be a reason for such symptoms. This study aimed to determine the vitamin D level among patients with unexplained MSK symptoms.
Methods: A cross-sectional study was conducted in a private clinic of Chattogram city, Bangladesh. A total of 110 unexplained MSK patients were enrolled conveniently. MSK symptoms were assessed by rheumatologist and serum vitamin D levels were measured according to the standard laboratory procedure. Descriptive and logistic regression analyses were done. Principal component analysis was performed for the reduction of MSK symptoms.
Results: The median (interquartile range) vitamin D level was 24.6 (20.0–29.0) ng/mL. Hypovitaminosis D (<30 ng/mL) was observed in 80.0% (95% CI: 71.3%–87.0%) respondents. Patients who had difficulty in climbing stairs, bone pain and muscle cramp had 79.8%, 84.9% and 79.8% hypovitaminosis D respectively. In logistic regression analysis, overweight defined by body mass index ≥25 kg/m2 (OR 5.5, 95% CI 1.7–17.4) was significantly associated with hypovitaminosis D.
Conclusions: Hypovitaminosis D was common in patients with unexplained MSK symptoms and overweight was significantly associated with it. Further studies in representative samples are necessary.
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| first_indexed | 2024-03-08T08:04:04Z |
| format | Article |
| id | doaj.art-eafc055ceefe4c3f96efb4c2845d1da0 |
| institution | Directory Open Access Journal |
| issn | 2074-2908 2224-7750 |
| language | English |
| last_indexed | 2024-03-08T08:04:04Z |
| publishDate | 2023-12-01 |
| publisher | Bangabandhu Sheikh Mujib Medical University |
| record_format | Article |
| series | Bangabandhu Sheikh Mujib Medical University Journal |
| spelling | doaj.art-eafc055ceefe4c3f96efb4c2845d1da02024-02-02T11:41:07ZengBangabandhu Sheikh Mujib Medical UniversityBangabandhu Sheikh Mujib Medical University Journal2074-29082224-77502023-12-01164Vitamin D level among patients with unexplained musculoskeletal symptomsMd. Abdur Razzaque0Iftekhar Hussain Bandhan1Rijwan Bhuiyan2Mohammad Ziaul Haider3Mirza Nurul Karim4Minhaj Rahim Choudhury5Department of Rheumatology, Chittagong Medical College, Chattogram, Bangladesh, Email: rhrazzaq@gmail.comDepartment of Rheumatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, Email: ibandhan@gmail.comDepartment of Epidemiology, Ekhlaspur Centre of Health, Chandpur, Bangladesh, Email: physiorijwan@gmail.comDepartment of Rheumatology, Rajshahi Medical College, Rajshahi, Bangladesh, Email: drziaulhaider@hotmail.comDepartment of Rheumatology, Chittagong Medical College, Chattogram, Bangladesh, Email: rhrazzaq@gmail.comDepartment of Rheumatology, Bangabandhu Sheikh Mujib Medical University, Dhaka, Bangladesh, Email: drminhaj11@gmail.com Background: Unexplained musculoskeletal (MSK) symptoms sometimes pose diagnostic and management challenges and can lead to prolonged suffering and disability. Hypovitaminosis D could be a reason for such symptoms. This study aimed to determine the vitamin D level among patients with unexplained MSK symptoms. Methods: A cross-sectional study was conducted in a private clinic of Chattogram city, Bangladesh. A total of 110 unexplained MSK patients were enrolled conveniently. MSK symptoms were assessed by rheumatologist and serum vitamin D levels were measured according to the standard laboratory procedure. Descriptive and logistic regression analyses were done. Principal component analysis was performed for the reduction of MSK symptoms. Results: The median (interquartile range) vitamin D level was 24.6 (20.0–29.0) ng/mL. Hypovitaminosis D (<30 ng/mL) was observed in 80.0% (95% CI: 71.3%–87.0%) respondents. Patients who had difficulty in climbing stairs, bone pain and muscle cramp had 79.8%, 84.9% and 79.8% hypovitaminosis D respectively. In logistic regression analysis, overweight defined by body mass index ≥25 kg/m2 (OR 5.5, 95% CI 1.7–17.4) was significantly associated with hypovitaminosis D. Conclusions: Hypovitaminosis D was common in patients with unexplained MSK symptoms and overweight was significantly associated with it. Further studies in representative samples are necessary. https://www.banglajol.info/index.php/BSMMUJ/article/view/70186Vitamin Dhypovitaminosis Dunexplained MSK symptoms musculoskeletal symptoms |
| spellingShingle | Md. Abdur Razzaque Iftekhar Hussain Bandhan Rijwan Bhuiyan Mohammad Ziaul Haider Mirza Nurul Karim Minhaj Rahim Choudhury Vitamin D level among patients with unexplained musculoskeletal symptoms Bangabandhu Sheikh Mujib Medical University Journal Vitamin D hypovitaminosis D unexplained MSK symptoms musculoskeletal symptoms |
| title | Vitamin D level among patients with unexplained musculoskeletal symptoms |
| title_full | Vitamin D level among patients with unexplained musculoskeletal symptoms |
| title_fullStr | Vitamin D level among patients with unexplained musculoskeletal symptoms |
| title_full_unstemmed | Vitamin D level among patients with unexplained musculoskeletal symptoms |
| title_short | Vitamin D level among patients with unexplained musculoskeletal symptoms |
| title_sort | vitamin d level among patients with unexplained musculoskeletal symptoms |
| topic | Vitamin D hypovitaminosis D unexplained MSK symptoms musculoskeletal symptoms |
| url | https://www.banglajol.info/index.php/BSMMUJ/article/view/70186 |
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