The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional study
Objective: To determine the characteristics and risk factors of breast cancer patients in a tertiary care setting. Method: The retrospective, cross-sectional study was conducted at the Sindh Institute of Urology and Transplantation, Karachi, and comprised data of all patients diagnosed with breas...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Pakistan Medical Association
2024-03-01
|
| Series: | Journal of the Pakistan Medical Association |
| Subjects: | |
| Online Access: | https://www.ojs.jpma.org.pk/index.php/public_html/article/view/9360 |
| _version_ | 1797244809559146496 |
|---|---|
| author | Bushra Shirazi Murk Niaz Muhammad Arsalan Khan |
| author_facet | Bushra Shirazi Murk Niaz Muhammad Arsalan Khan |
| author_sort | Bushra Shirazi |
| collection | DOAJ |
| description |
Objective: To determine the characteristics and risk factors of breast cancer patients in a tertiary care setting.
Method: The retrospective, cross-sectional study was conducted at the Sindh Institute of Urology and Transplantation, Karachi, and comprised data of all patients diagnosed with breast cancer from March 2017 to December 2021. Demographic characteristics, clinical presentation, stage of the disease and histopathological characteristics were noted. Data related too all the variables was not available in all cases. Data was analysed using SPSS 23.
Results: Of the 690 patients, 683(99%) were females and 7(1%) were males. The mean age at presentation was 49.3±13.5 years, while the mean duration of symptoms was 10.24±17.64) months. Most of the females were married 642(93%) and multiparous 484(70.9%), while 293(42.5%) had breastfed their children for >1 year, and 412(59.7%) had no history of contraception use. The most common stage at presentation was stage II (48.6%), and most patients had grade II 395(57.2%) invasive ductal carcinoma, with Luminal A molecular subtype noted in 287(41.6%) cases.
Conclusion: The characteristics of breast cancer in the sample had certain distinctions compared to other populations. It is important to integrate all datasets and develop guidelines appropriate to Pakistani population.
Key Words: Breast cancer, Risk factor, Clinical audits, Disease attribute, Medical oncology, Carcinoma.
|
| first_indexed | 2024-04-24T19:16:55Z |
| format | Article |
| id | doaj.art-eb00eca6a29045df97c0c3690768fe75 |
| institution | Directory Open Access Journal |
| issn | 0030-9982 |
| language | English |
| last_indexed | 2024-04-24T19:16:55Z |
| publishDate | 2024-03-01 |
| publisher | Pakistan Medical Association |
| record_format | Article |
| series | Journal of the Pakistan Medical Association |
| spelling | doaj.art-eb00eca6a29045df97c0c3690768fe752024-03-26T05:37:01ZengPakistan Medical AssociationJournal of the Pakistan Medical Association0030-99822024-03-0174410.47391/JPMA.9360The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional studyBushra Shirazi0Murk Niaz1Muhammad Arsalan Khan2Department of General Surgery, Sindh Institute of Urology and Transplantation, Karachi, PakistanDepartment of Neurosurgery, Civil Hospital, Karachi, PakistanDepartment of General Surgery, Sindh Institute of Urology and Transplantation, Karachi, Pakistan Objective: To determine the characteristics and risk factors of breast cancer patients in a tertiary care setting. Method: The retrospective, cross-sectional study was conducted at the Sindh Institute of Urology and Transplantation, Karachi, and comprised data of all patients diagnosed with breast cancer from March 2017 to December 2021. Demographic characteristics, clinical presentation, stage of the disease and histopathological characteristics were noted. Data related too all the variables was not available in all cases. Data was analysed using SPSS 23. Results: Of the 690 patients, 683(99%) were females and 7(1%) were males. The mean age at presentation was 49.3±13.5 years, while the mean duration of symptoms was 10.24±17.64) months. Most of the females were married 642(93%) and multiparous 484(70.9%), while 293(42.5%) had breastfed their children for >1 year, and 412(59.7%) had no history of contraception use. The most common stage at presentation was stage II (48.6%), and most patients had grade II 395(57.2%) invasive ductal carcinoma, with Luminal A molecular subtype noted in 287(41.6%) cases. Conclusion: The characteristics of breast cancer in the sample had certain distinctions compared to other populations. It is important to integrate all datasets and develop guidelines appropriate to Pakistani population. Key Words: Breast cancer, Risk factor, Clinical audits, Disease attribute, Medical oncology, Carcinoma. https://www.ojs.jpma.org.pk/index.php/public_html/article/view/9360Breast cancerRisk factorClinical auditsDisease attributeMedical oncologyCarcinoma |
| spellingShingle | Bushra Shirazi Murk Niaz Muhammad Arsalan Khan The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional study Journal of the Pakistan Medical Association Breast cancer Risk factor Clinical audits Disease attribute Medical oncology Carcinoma |
| title | The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional study |
| title_full | The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional study |
| title_fullStr | The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional study |
| title_full_unstemmed | The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional study |
| title_short | The characteristics and risk factors of breast cancer patients trend distinctive regional differences: a cross-sectional study |
| title_sort | characteristics and risk factors of breast cancer patients trend distinctive regional differences a cross sectional study |
| topic | Breast cancer Risk factor Clinical audits Disease attribute Medical oncology Carcinoma |
| url | https://www.ojs.jpma.org.pk/index.php/public_html/article/view/9360 |
| work_keys_str_mv | AT bushrashirazi thecharacteristicsandriskfactorsofbreastcancerpatientstrenddistinctiveregionaldifferencesacrosssectionalstudy AT murkniaz thecharacteristicsandriskfactorsofbreastcancerpatientstrenddistinctiveregionaldifferencesacrosssectionalstudy AT muhammadarsalankhan thecharacteristicsandriskfactorsofbreastcancerpatientstrenddistinctiveregionaldifferencesacrosssectionalstudy AT bushrashirazi characteristicsandriskfactorsofbreastcancerpatientstrenddistinctiveregionaldifferencesacrosssectionalstudy AT murkniaz characteristicsandriskfactorsofbreastcancerpatientstrenddistinctiveregionaldifferencesacrosssectionalstudy AT muhammadarsalankhan characteristicsandriskfactorsofbreastcancerpatientstrenddistinctiveregionaldifferencesacrosssectionalstudy |