Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution

Stoichiometric interactions explain spindle dynamics and scaling across 100 million years of nematode evolution

The spindle shows remarkable diversity, and changes in an integrated fashion, as cells vary over evolution. Here, we provide a mechanistic explanation for variations in the first mitotic spindle in nematodes. We used a combination of quantitative genetics and biophysics to rule out broad classes of...

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Những tác giả chính: Reza Farhadifar, Che-Hang Yu, Gunar Fabig, Hai-Yin Wu, David B Stein, Matthew Rockman, Thomas Müller-Reichert, Michael J Shelley, Daniel J Needleman
Định dạng: Bài viết
Ngôn ngữ:English
Được phát hành: eLife Sciences Publications Ltd 2020-09-01
Loạt:eLife
Những chủ đề:
cell division
mitotic spindle
scaling
QTL mapping
mathematical modeling
cortical forces
Truy cập trực tuyến:https://elifesciences.org/articles/55877

Internet

https://elifesciences.org/articles/55877

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