Five-Year Survival Analysis of Renal Transplantation Graft and Affecting Factors
Background: Renal transplantation is the appropriate and most effective therapeutic strategy for patients with end-stage renal disease. The aim of this study was to determine the five-year survival rate of renal transplantation graft and affecting factors. Methods: A survival analysis study was per...
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| Format: | Article |
| Language: | fas |
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Isfahan University of Medical Sciences
2014-06-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/3078 |
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| author | Amir Hossein Hashemian Behrouz Beiranvand Mansour Rezaei Amin Roshani-Sheykhabad Abdolrasol Bardideh |
| author_facet | Amir Hossein Hashemian Behrouz Beiranvand Mansour Rezaei Amin Roshani-Sheykhabad Abdolrasol Bardideh |
| author_sort | Amir Hossein Hashemian |
| collection | DOAJ |
| description | Background: Renal transplantation is the appropriate and most effective therapeutic strategy for patients with end-stage renal disease. The aim of this study was to determine the five-year survival rate of renal transplantation graft and affecting factors.
Methods: A survival analysis study was performed on the data of 756 renal transplants in Kermanshah, Iran, during 2001 to 2012. Kaplan-Meier, Cox regression methods and log-rank tests were used to estimate the graft survival rate and comparison of cumulative survival difference between the groups was done using STATA software.
Findings: Via Kaplan-Meier method, the estimated survival rate of grafts at six months and one, three and five years were 89.0, 87.4, 80.0 and 75.0 percent, respectively. Cox regression model showed that the variables of kinship, donor and recipient sex, and after-surgery creatinine and hemoglobin levels were significantly associated with graft survival rate.
Conclusion: The five-year survival rate was 75.0% for renal transplants in the studied center, does not seem satisfactory compared with reported rates of major transplant centers. |
| first_indexed | 2024-03-12T09:49:37Z |
| format | Article |
| id | doaj.art-eb0b1dff7d8c41429ad1fc6194a07d68 |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T09:49:37Z |
| publishDate | 2014-06-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-eb0b1dff7d8c41429ad1fc6194a07d682023-09-02T12:40:29ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2014-06-01322835505571587Five-Year Survival Analysis of Renal Transplantation Graft and Affecting FactorsAmir Hossein Hashemian0Behrouz Beiranvand1Mansour Rezaei2Amin Roshani-Sheykhabad3Abdolrasol Bardideh4Assistant Professor, Department of Biostatistics and Epidemiology, School of Public Health AND Research Center for Environmental Determinants of Health (RCEDH), Kermanshah University of Medical Sciences, Kermanshah, IranMSc Student, Department of Biostatistics and Epidemiology, School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, IranAssistant Professor, Department of Biostatistics and Epidemiology, School of Public Health, Kermanshah University of Medical Sciences, Kermanshah, IranMSc Student, Department of Statistics, School of Basic Sciences, Shahid Beheshti University, Tehran, IranAssistant Professor, Department of Nephrology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, IranBackground: Renal transplantation is the appropriate and most effective therapeutic strategy for patients with end-stage renal disease. The aim of this study was to determine the five-year survival rate of renal transplantation graft and affecting factors. Methods: A survival analysis study was performed on the data of 756 renal transplants in Kermanshah, Iran, during 2001 to 2012. Kaplan-Meier, Cox regression methods and log-rank tests were used to estimate the graft survival rate and comparison of cumulative survival difference between the groups was done using STATA software. Findings: Via Kaplan-Meier method, the estimated survival rate of grafts at six months and one, three and five years were 89.0, 87.4, 80.0 and 75.0 percent, respectively. Cox regression model showed that the variables of kinship, donor and recipient sex, and after-surgery creatinine and hemoglobin levels were significantly associated with graft survival rate. Conclusion: The five-year survival rate was 75.0% for renal transplants in the studied center, does not seem satisfactory compared with reported rates of major transplant centers.http://jims.mui.ac.ir/index.php/jims/article/view/3078Kidney transplantationGraft survivalCox regression |
| spellingShingle | Amir Hossein Hashemian Behrouz Beiranvand Mansour Rezaei Amin Roshani-Sheykhabad Abdolrasol Bardideh Five-Year Survival Analysis of Renal Transplantation Graft and Affecting Factors مجله دانشکده پزشکی اصفهان Kidney transplantation Graft survival Cox regression |
| title | Five-Year Survival Analysis of Renal Transplantation Graft and Affecting Factors |
| title_full | Five-Year Survival Analysis of Renal Transplantation Graft and Affecting Factors |
| title_fullStr | Five-Year Survival Analysis of Renal Transplantation Graft and Affecting Factors |
| title_full_unstemmed | Five-Year Survival Analysis of Renal Transplantation Graft and Affecting Factors |
| title_short | Five-Year Survival Analysis of Renal Transplantation Graft and Affecting Factors |
| title_sort | five year survival analysis of renal transplantation graft and affecting factors |
| topic | Kidney transplantation Graft survival Cox regression |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/3078 |
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