Comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitis
Inflammatory diseases of the sinuses – one of the most common nosologies in the practice of otorhinolaryngologist; its pathogenesis is well studied, and treatment recommendations are detailed. Following them, however, cannot completely prevent chronic disease or recurrence. Antimicrobial photodynami...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | Russian |
| Published: |
Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"
2019-07-01
|
| Series: | Biomedical Photonics |
| Subjects: | |
| Online Access: | https://www.pdt-journal.com/jour/article/view/313 |
| _version_ | 1826559568882171904 |
|---|---|
| author | G. P. Popova Yu. A. Nakatis M. A. Rymsha |
| author_facet | G. P. Popova Yu. A. Nakatis M. A. Rymsha |
| author_sort | G. P. Popova |
| collection | DOAJ |
| description | Inflammatory diseases of the sinuses – one of the most common nosologies in the practice of otorhinolaryngologist; its pathogenesis is well studied, and treatment recommendations are detailed. Following them, however, cannot completely prevent chronic disease or recurrence. Antimicrobial photodynamic therapy is a promising method of treating sinusitis, which has proved its effectiveness, but has not yet been widely used. This work describes our experience in photodynamic therapy with chlorin e6 of chronic sinusitis using a new laser diode-based irradiation source. For patients who had previous sinus surgery an adapter for penetration into the sinus through anastomosis was developed and tested. First group of the patients underwent photodynamic therapy (PDT) according to the conventional scheme, using a laser with a wavelength of 662 nm; while the second one underwent PDT using a 405 nm laser. With daily washing of the nasal sinus, the period of inflammation relief (evaluated by the absence of pathological discharge during washing) amounted to 3.8 full days on average in the first group of patients, compared to 5.4 days on average for the second group. We carried out the comparative analysis of the treatment results based on clinical assessment and radiological evaluation (CT) at the time of discharge from the hospital and 1 month later. |
| first_indexed | 2024-04-10T03:55:31Z |
| format | Article |
| id | doaj.art-eb0dcd6c7d79490ca7f9af84d740096d |
| institution | Directory Open Access Journal |
| issn | 2413-9432 |
| language | Russian |
| last_indexed | 2025-03-14T09:02:28Z |
| publishDate | 2019-07-01 |
| publisher | Non-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association" |
| record_format | Article |
| series | Biomedical Photonics |
| spelling | doaj.art-eb0dcd6c7d79490ca7f9af84d740096d2025-03-02T12:41:33ZrusNon-profit partnership for development of domestic photodynamic therapy and photodiagnosis "Russian Photodynamic Association"Biomedical Photonics2413-94322019-07-0182141810.24931/2413-9432-2019-8-2-14-18168Comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitisG. P. Popova0Yu. A. Nakatis1M. A. Rymsha2Saint-Petersburg State University; JSC “Admiralty Shipyards”Saint-Petersburg State University; Clinical Hospital No. 122 named after L. G. Sokolov FMBASaint-Petersburg State University; Clinical Hospital No. 122 named after L. G. Sokolov FMBAInflammatory diseases of the sinuses – one of the most common nosologies in the practice of otorhinolaryngologist; its pathogenesis is well studied, and treatment recommendations are detailed. Following them, however, cannot completely prevent chronic disease or recurrence. Antimicrobial photodynamic therapy is a promising method of treating sinusitis, which has proved its effectiveness, but has not yet been widely used. This work describes our experience in photodynamic therapy with chlorin e6 of chronic sinusitis using a new laser diode-based irradiation source. For patients who had previous sinus surgery an adapter for penetration into the sinus through anastomosis was developed and tested. First group of the patients underwent photodynamic therapy (PDT) according to the conventional scheme, using a laser with a wavelength of 662 nm; while the second one underwent PDT using a 405 nm laser. With daily washing of the nasal sinus, the period of inflammation relief (evaluated by the absence of pathological discharge during washing) amounted to 3.8 full days on average in the first group of patients, compared to 5.4 days on average for the second group. We carried out the comparative analysis of the treatment results based on clinical assessment and radiological evaluation (CT) at the time of discharge from the hospital and 1 month later.https://www.pdt-journal.com/jour/article/view/313chronic sinusitisantibacterial photodynamic therapydiode laser |
| spellingShingle | G. P. Popova Yu. A. Nakatis M. A. Rymsha Comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitis Biomedical Photonics chronic sinusitis antibacterial photodynamic therapy diode laser |
| title | Comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitis |
| title_full | Comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitis |
| title_fullStr | Comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitis |
| title_full_unstemmed | Comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitis |
| title_short | Comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitis |
| title_sort | comparison of photodynamic therapy efficiency using radiation sources with different wavelengths in the treatment of sinusitis |
| topic | chronic sinusitis antibacterial photodynamic therapy diode laser |
| url | https://www.pdt-journal.com/jour/article/view/313 |
| work_keys_str_mv | AT gppopova comparisonofphotodynamictherapyefficiencyusingradiationsourceswithdifferentwavelengthsinthetreatmentofsinusitis AT yuanakatis comparisonofphotodynamictherapyefficiencyusingradiationsourceswithdifferentwavelengthsinthetreatmentofsinusitis AT marymsha comparisonofphotodynamictherapyefficiencyusingradiationsourceswithdifferentwavelengthsinthetreatmentofsinusitis |