Duration of the determination of specific Igm antibodies in primary syphilis patients after treatment

It was carried out a study with ALISAIgM of 341 samples of the blood, obtained from the patients with the early forms of syphilis 3-36 months later the end of adequate antibacterial therapy with the purpose for studying the duration of circulation in the blood of specific antibodies IgM to the antig...

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Main Authors: S. V. Rotanov, F. A. Ermatova
Format: Article
Language:English
Published: State Scientific Center of Dermatovenereology and Cosmetology 2017-08-01
Series:Vestnik Dermatologii i Venerologii
Subjects:
Online Access:https://www.vestnikdv.ru/jour/article/view/131
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author S. V. Rotanov
F. A. Ermatova
author_facet S. V. Rotanov
F. A. Ermatova
author_sort S. V. Rotanov
collection DOAJ
description It was carried out a study with ALISAIgM of 341 samples of the blood, obtained from the patients with the early forms of syphilis 3-36 months later the end of adequate antibacterial therapy with the purpose for studying the duration of circulation in the blood of specific antibodies IgM to the antigens T. pallidum after the treatment. It was shown gradual reduction of the levels of the anti-treponema antibodies of the class M in the blood with an increase of the period of observation and their total elimination to the period of 36 months. It was not established reliable differences within the dynamics of a decrease in the levels of specific IgM and the periods of negativation of the ALISAIgM results depending on the adequate method of antibacterial therapy.
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spelling doaj.art-eb1364e4617844c996a10cc035bff0d92023-09-02T07:11:44ZengState Scientific Center of Dermatovenereology and CosmetologyVestnik Dermatologii i Venerologii0042-46092313-62942017-08-010211612110.25208/0042-4609-2015-0-2-116-121130Duration of the determination of specific Igm antibodies in primary syphilis patients after treatmentS. V. Rotanov0F. A. Ermatova1State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation; The Russian National Research Medical University named after N.I. PirogovThe Russian National Research Medical University named after N.I. PirogovIt was carried out a study with ALISAIgM of 341 samples of the blood, obtained from the patients with the early forms of syphilis 3-36 months later the end of adequate antibacterial therapy with the purpose for studying the duration of circulation in the blood of specific antibodies IgM to the antigens T. pallidum after the treatment. It was shown gradual reduction of the levels of the anti-treponema antibodies of the class M in the blood with an increase of the period of observation and their total elimination to the period of 36 months. It was not established reliable differences within the dynamics of a decrease in the levels of specific IgM and the periods of negativation of the ALISAIgM results depending on the adequate method of antibacterial therapy.https://www.vestnikdv.ru/jour/article/view/131сифилисклинико-серологическое наблюдениеиммуноферментный анализиммуноглобулины класса msyphilisserological observationimmunoenzyme analysisthe immunoglobulin of class m
spellingShingle S. V. Rotanov
F. A. Ermatova
Duration of the determination of specific Igm antibodies in primary syphilis patients after treatment
Vestnik Dermatologii i Venerologii
сифилис
клинико-серологическое наблюдение
иммуноферментный анализ
иммуноглобулины класса m
syphilis
serological observation
immunoenzyme analysis
the immunoglobulin of class m
title Duration of the determination of specific Igm antibodies in primary syphilis patients after treatment
title_full Duration of the determination of specific Igm antibodies in primary syphilis patients after treatment
title_fullStr Duration of the determination of specific Igm antibodies in primary syphilis patients after treatment
title_full_unstemmed Duration of the determination of specific Igm antibodies in primary syphilis patients after treatment
title_short Duration of the determination of specific Igm antibodies in primary syphilis patients after treatment
title_sort duration of the determination of specific igm antibodies in primary syphilis patients after treatment
topic сифилис
клинико-серологическое наблюдение
иммуноферментный анализ
иммуноглобулины класса m
syphilis
serological observation
immunoenzyme analysis
the immunoglobulin of class m
url https://www.vestnikdv.ru/jour/article/view/131
work_keys_str_mv AT svrotanov durationofthedeterminationofspecificigmantibodiesinprimarysyphilispatientsaftertreatment
AT faermatova durationofthedeterminationofspecificigmantibodiesinprimarysyphilispatientsaftertreatment