METTL3 promotes osteoblast ribosome biogenesis and alleviates periodontitis

METTL3 promotes osteoblast ribosome biogenesis and alleviates periodontitis

Abstract Background Periodontitis is a highly prevalent oral disease characterized by bacterium-induced periodontal inflammation and alveolar bone destruction. Osteoblast function is impaired in periodontitis with a global proteome change. METTL3 is the pivotal methyltransferase of N 6-methyladenosi...

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Bibliographic Details
Main Authors: Yiwen Zhang, Yiping Kong, Wenjie Zhang, Jinlin He, Zhanqi Zhang, Yongjie Cai, Yiqing Zhao, Qiong Xu
Format: Article
Language:English
Published: BMC 2024-01-01
Series:Clinical Epigenetics
Subjects:
Periodontitis
Osteoblast
Ribosome biogenesis
METTL3
Online Access:https://doi.org/10.1186/s13148-024-01628-8

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