Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating Scale

Mastectomy is a breast cancer surgery procedure that can lead to acute postoperative pain with 20–30% of patients may progress to postmastectomy chronic pain syndrome (PMPS). Therefore, it is necessary provide an adequate pain management so patients will not experience episodes of pain that can disr...

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Bibliographic Details
Main Authors: Roni D. Kartapraja, Iwan Fuadi, Ike Sri Redjeki
Format: Article
Language:Indonesian
Published: Universitas Padjadjaran 2016-08-01
Series:Jurnal Anestesi Perioperatif
Subjects:
Online Access:http://journal.fk.unpad.ac.id/index.php/jap/article/view/825
Description
Summary:Mastectomy is a breast cancer surgery procedure that can lead to acute postoperative pain with 20–30% of patients may progress to postmastectomy chronic pain syndrome (PMPS). Therefore, it is necessary provide an adequate pain management so patients will not experience episodes of pain that can disrupt their productivity. The purpose of this study was to compare the effect of preemptive analgesia parecoxib with paracetamol in reducing radical mastectomy postoperative pain.The study was a prospective single blinded randomized controlled clinical trials on 30 adult patients who underwent radical mastectomy surgery in Dr. Hasan Sadikin General Hospital between September and November 2014. Subjects were divided randomly into two groups, 1 gram paracetamol preemptive analgesia and 40 miligram parecoxib which given 30 minutes before the first incision has been made. After the surgery was completed, we record the pain scale using the numeric rating scale (NRS). The data were recorded starting from the recovery room to 12 hours postoperative in the ward. Statistical analysis was performed using the t-test with statistical package for social science (SPSS) version 21.0 for Windows software. The results showed that the 40 miligram parecoxib preemptive analgesia group required longer rescue analgesics and lowerNRS than 1 gram paracetamol preemptive analgesia (p<0.05). In conclusion, 40 miligram parecoxib preemptive analgesia is better than 1 gram paracetamol preemptive analgesia in reducing radical mastectomy postoperative pain according to numeric rating scale.
ISSN:2337-7909
2338-8463