Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating Scale

Mastectomy is a breast cancer surgery procedure that can lead to acute postoperative pain with 20–30% of patients may progress to postmastectomy chronic pain syndrome (PMPS). Therefore, it is necessary provide an adequate pain management so patients will not experience episodes of pain that can disr...

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Main Authors: Roni D. Kartapraja, Iwan Fuadi, Ike Sri Redjeki
Format: Article
Language:Indonesian
Published: Universitas Padjadjaran 2016-08-01
Series:Jurnal Anestesi Perioperatif
Subjects:
Online Access:http://journal.fk.unpad.ac.id/index.php/jap/article/view/825
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author Roni D. Kartapraja
Iwan Fuadi
Ike Sri Redjeki
author_facet Roni D. Kartapraja
Iwan Fuadi
Ike Sri Redjeki
author_sort Roni D. Kartapraja
collection DOAJ
description Mastectomy is a breast cancer surgery procedure that can lead to acute postoperative pain with 20–30% of patients may progress to postmastectomy chronic pain syndrome (PMPS). Therefore, it is necessary provide an adequate pain management so patients will not experience episodes of pain that can disrupt their productivity. The purpose of this study was to compare the effect of preemptive analgesia parecoxib with paracetamol in reducing radical mastectomy postoperative pain.The study was a prospective single blinded randomized controlled clinical trials on 30 adult patients who underwent radical mastectomy surgery in Dr. Hasan Sadikin General Hospital between September and November 2014. Subjects were divided randomly into two groups, 1 gram paracetamol preemptive analgesia and 40 miligram parecoxib which given 30 minutes before the first incision has been made. After the surgery was completed, we record the pain scale using the numeric rating scale (NRS). The data were recorded starting from the recovery room to 12 hours postoperative in the ward. Statistical analysis was performed using the t-test with statistical package for social science (SPSS) version 21.0 for Windows software. The results showed that the 40 miligram parecoxib preemptive analgesia group required longer rescue analgesics and lowerNRS than 1 gram paracetamol preemptive analgesia (p<0.05). In conclusion, 40 miligram parecoxib preemptive analgesia is better than 1 gram paracetamol preemptive analgesia in reducing radical mastectomy postoperative pain according to numeric rating scale.
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spelling doaj.art-eb2e17e765bc45a9b3baf4aba18590fc2022-12-21T19:01:10ZindUniversitas PadjadjaranJurnal Anestesi Perioperatif2337-79092338-84632016-08-014211111610.15851/jap.v4n2.825Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating ScaleRoni D. Kartapraja0 Iwan Fuadi1 Ike Sri Redjeki2Departemen Anestesiologi dan Terapi Intensif/Rumah Sakit Umum Daerah Bayu Asih PurwakartaDepartemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Padjadjaran/Rumah Sakit Dr. Hasan Sadikin BandungDepartemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Padjadjaran/Rumah Sakit Dr. Hasan Sadikin BandungMastectomy is a breast cancer surgery procedure that can lead to acute postoperative pain with 20–30% of patients may progress to postmastectomy chronic pain syndrome (PMPS). Therefore, it is necessary provide an adequate pain management so patients will not experience episodes of pain that can disrupt their productivity. The purpose of this study was to compare the effect of preemptive analgesia parecoxib with paracetamol in reducing radical mastectomy postoperative pain.The study was a prospective single blinded randomized controlled clinical trials on 30 adult patients who underwent radical mastectomy surgery in Dr. Hasan Sadikin General Hospital between September and November 2014. Subjects were divided randomly into two groups, 1 gram paracetamol preemptive analgesia and 40 miligram parecoxib which given 30 minutes before the first incision has been made. After the surgery was completed, we record the pain scale using the numeric rating scale (NRS). The data were recorded starting from the recovery room to 12 hours postoperative in the ward. Statistical analysis was performed using the t-test with statistical package for social science (SPSS) version 21.0 for Windows software. The results showed that the 40 miligram parecoxib preemptive analgesia group required longer rescue analgesics and lowerNRS than 1 gram paracetamol preemptive analgesia (p<0.05). In conclusion, 40 miligram parecoxib preemptive analgesia is better than 1 gram paracetamol preemptive analgesia in reducing radical mastectomy postoperative pain according to numeric rating scale.http://journal.fk.unpad.ac.id/index.php/jap/article/view/825Numeric rating scaleparacetamolparecoxibpostoperative painpreemptive analgesiaradical mastectomy
spellingShingle Roni D. Kartapraja
Iwan Fuadi
Ike Sri Redjeki
Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating Scale
Jurnal Anestesi Perioperatif
Numeric rating scale
paracetamol
parecoxib
postoperative pain
preemptive analgesia
radical mastectomy
title Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating Scale
title_full Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating Scale
title_fullStr Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating Scale
title_full_unstemmed Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating Scale
title_short Perbandingan Efek Pemberian Analgesia Pre-emtif Parecoxib dengan Parasetamol terhadap Nyeri Pascaoperasi Radikal Mastektomi Menggunakan Numeric Rating Scale
title_sort perbandingan efek pemberian analgesia pre emtif parecoxib dengan parasetamol terhadap nyeri pascaoperasi radikal mastektomi menggunakan numeric rating scale
topic Numeric rating scale
paracetamol
parecoxib
postoperative pain
preemptive analgesia
radical mastectomy
url http://journal.fk.unpad.ac.id/index.php/jap/article/view/825
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