Attenuation of immune activation in patients with multiple sclerosis on a wheat-reduced diet: a pilot crossover trial

Background: Western lifestyle has been associated with an increase in relapsing–remitting multiple sclerosis (RRMS). In mice, dietary wheat amylase–trypsin inhibitors (ATIs) activate intestinal myeloid cells and augment T cell-mediated systemic inflammation. Objective: The aim of this study was to a...

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Bibliographic Details
Main Authors: Sinah Engel, Luisa Klotz, Timo Wirth, Ann-Katrin Fleck, Geethanjali Pickert, Melanie Eschborn, Samia Kreuzburg, Valentina Curella, Stefan Bittner, Frauke Zipp, Detlef Schuppan, Felix Luessi
Format: Article
Language:English
Published: SAGE Publishing 2023-06-01
Series:Therapeutic Advances in Neurological Disorders
Online Access:https://doi.org/10.1177/17562864231170928