Tumor Microenvironment as a Regulator of Radiation Therapy: New Insights into Stromal-Mediated Radioresistance

Tumor Microenvironment as a Regulator of Radiation Therapy: New Insights into Stromal-Mediated Radioresistance

A tumor is a complex “organ” composed of malignant cancer cells harboring genetic aberrations surrounded by a stroma comprised of non-malignant cells and an extracellular matrix. Considerable evidence has demonstrated that components of the genetically “normal” tumor stroma contribute to tumor progr...

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Bibliographic Details
Main Authors:	Varintra E. Krisnawan, Jennifer A. Stanley, Julie K. Schwarz, David G. DeNardo
Format:	Article
Language:	English
Published:	MDPI AG 2020-10-01
Series:	Cancers
Subjects:	stroma cancer-associated fibroblast (CAF) extracellular matrix (ECM) cytokine/chemokine growth factors pro- and anti-tumor immune cells
Online Access:	https://www.mdpi.com/2072-6694/12/10/2916

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