Updates on the Virulence Factors Produced by Multidrug-Resistant <i>Enterobacterales</i> and Strategies to Control Their Infections
The <i>Enterobacterales</i> order is a massive group of Gram-negative bacteria comprised of pathogenic and nonpathogenic members, including beneficial commensal gut microbiota. The pathogenic members produce several pathogenic or virulence factors that enhance their pathogenic properties...
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| Format: | Article |
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MDPI AG
2023-07-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/11/8/1901 |
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| author | Mohd W. Azam Raffaele Zarrilli Asad U. Khan |
| author_facet | Mohd W. Azam Raffaele Zarrilli Asad U. Khan |
| author_sort | Mohd W. Azam |
| collection | DOAJ |
| description | The <i>Enterobacterales</i> order is a massive group of Gram-negative bacteria comprised of pathogenic and nonpathogenic members, including beneficial commensal gut microbiota. The pathogenic members produce several pathogenic or virulence factors that enhance their pathogenic properties and increase the severity of the infection. The members of <i>Enterobacterales</i> can also develop resistance against the common antimicrobial agents, a phenomenon called antimicrobial resistance (AMR). Many pathogenic <i>Enterobacterales</i> members are known to possess antimicrobial resistance. This review discusses the virulence factors, pathogenicity, and infections caused by multidrug-resistant <i>Enterobacterales</i>, especially <i>E. coli</i> and some other bacterial species sharing similarities with the <i>Enterobacterales</i> members. We also discuss both conventional and modern approaches used to combat the infections caused by them. Understanding the virulence factors produced by the pathogenic bacteria will help develop novel strategies and methods to treat infections caused by them. |
| first_indexed | 2024-03-10T23:44:07Z |
| format | Article |
| id | doaj.art-eb3330ca7c0c4eafbfcb4667ac55a35d |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-10T23:44:07Z |
| publishDate | 2023-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-eb3330ca7c0c4eafbfcb4667ac55a35d2023-11-19T02:15:43ZengMDPI AGMicroorganisms2076-26072023-07-01118190110.3390/microorganisms11081901Updates on the Virulence Factors Produced by Multidrug-Resistant <i>Enterobacterales</i> and Strategies to Control Their InfectionsMohd W. Azam0Raffaele Zarrilli1Asad U. Khan2Medical Microbiology and Molecular Biology Laboratory, Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, IndiaDepartment of Public Health, University of Naples Federico II, 80131 Naples, ItalyMedical Microbiology and Molecular Biology Laboratory, Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, IndiaThe <i>Enterobacterales</i> order is a massive group of Gram-negative bacteria comprised of pathogenic and nonpathogenic members, including beneficial commensal gut microbiota. The pathogenic members produce several pathogenic or virulence factors that enhance their pathogenic properties and increase the severity of the infection. The members of <i>Enterobacterales</i> can also develop resistance against the common antimicrobial agents, a phenomenon called antimicrobial resistance (AMR). Many pathogenic <i>Enterobacterales</i> members are known to possess antimicrobial resistance. This review discusses the virulence factors, pathogenicity, and infections caused by multidrug-resistant <i>Enterobacterales</i>, especially <i>E. coli</i> and some other bacterial species sharing similarities with the <i>Enterobacterales</i> members. We also discuss both conventional and modern approaches used to combat the infections caused by them. Understanding the virulence factors produced by the pathogenic bacteria will help develop novel strategies and methods to treat infections caused by them.https://www.mdpi.com/2076-2607/11/8/1901virulencemultidrug-resistance<i>Enterobacterales</i> |
| spellingShingle | Mohd W. Azam Raffaele Zarrilli Asad U. Khan Updates on the Virulence Factors Produced by Multidrug-Resistant <i>Enterobacterales</i> and Strategies to Control Their Infections Microorganisms virulence multidrug-resistance <i>Enterobacterales</i> |
| title | Updates on the Virulence Factors Produced by Multidrug-Resistant <i>Enterobacterales</i> and Strategies to Control Their Infections |
| title_full | Updates on the Virulence Factors Produced by Multidrug-Resistant <i>Enterobacterales</i> and Strategies to Control Their Infections |
| title_fullStr | Updates on the Virulence Factors Produced by Multidrug-Resistant <i>Enterobacterales</i> and Strategies to Control Their Infections |
| title_full_unstemmed | Updates on the Virulence Factors Produced by Multidrug-Resistant <i>Enterobacterales</i> and Strategies to Control Their Infections |
| title_short | Updates on the Virulence Factors Produced by Multidrug-Resistant <i>Enterobacterales</i> and Strategies to Control Their Infections |
| title_sort | updates on the virulence factors produced by multidrug resistant i enterobacterales i and strategies to control their infections |
| topic | virulence multidrug-resistance <i>Enterobacterales</i> |
| url | https://www.mdpi.com/2076-2607/11/8/1901 |
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