Association Between Young Adult Characteristics and Blood Pressure Trajectories
Background Blood pressure (BP) trajectories from young adulthood through middle age are associated with cardiovascular risk. We examined the associations of hypertension risk factors with BP trajectories among a large diverse sample. Methods and Results We analyzed data from young adults, aged 18 to...
| Main Authors: | , , , , , , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2024-04-01
|
| Series: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| Subjects: | |
| Online Access: | https://www.ahajournals.org/doi/10.1161/JAHA.123.033053 |
| _version_ | 1797205539522871296 |
|---|---|
| author | Jaejin An Heidi Fischer Liang Ni Mengying Xia Soon Kyu Choi Kerresa L. Morrissette Rong Wei Kristi Reynolds Paul Muntner Monika M. Safford Andrew E. Moran Brandon K. Bellows Carmen R. Isasi Norrina B. Allen Vanessa Xanthakis Lisandro D. Colantonio Yiyi Zhang |
| author_facet | Jaejin An Heidi Fischer Liang Ni Mengying Xia Soon Kyu Choi Kerresa L. Morrissette Rong Wei Kristi Reynolds Paul Muntner Monika M. Safford Andrew E. Moran Brandon K. Bellows Carmen R. Isasi Norrina B. Allen Vanessa Xanthakis Lisandro D. Colantonio Yiyi Zhang |
| author_sort | Jaejin An |
| collection | DOAJ |
| description | Background Blood pressure (BP) trajectories from young adulthood through middle age are associated with cardiovascular risk. We examined the associations of hypertension risk factors with BP trajectories among a large diverse sample. Methods and Results We analyzed data from young adults, aged 18 to 39 years, with untreated BP <140/90 mm Hg at baseline from Kaiser Permanente Southern California (N=355 324). We used latent growth curve models to identify 10‐year BP trajectories and to assess the associations between characteristics in young adulthood and BP trajectories. We identified the following 5 distinct systolic BP trajectories, which appeared to be determined mainly by the baseline BP with progressively higher BP at each year: group 1 (lowest BP trajectory, 7.9%), group 2 (26.5%), group 3 (33.0%), group 4 (25.4%), and group 5 (highest BP trajectory, 7.3%). Older age (adjusted odds ratio for 30–39 versus 18–29 years, 1.23 [95% CI, 1.18–1.28]), male sex (13.38 [95% CI, 12.80–13.99]), obesity (body mass index ≥30 versus 18.5–24.9 kg/m2, 14.81 [95% CI, 14.03–15.64]), overweight (body mass index 25–29.9 versus 18.5–24.9 kg/m2, 3.16 [95% CI, 3.00–3.33]), current smoking (1.58 [95% CI, 1.48–1.67]), prediabetes (1.21 [95% CI, 1.13–1.29]), diabetes (1.60 [95% CI, 1.41–1.81]) and high low‐density lipoprotein cholesterol (≥160 versus <100 mg/dL, 1.52 [95% CI, 1.37–1.68]) were associated with the highest BP trajectory (group 5) compared with the reference group (group 2). Conclusions Traditional hypertension risk factors including smoking, diabetes, and elevated lipids were associated with BP trajectories in young adults, with obesity having the strongest association with the highest BP trajectory group. |
| first_indexed | 2024-04-24T08:52:44Z |
| format | Article |
| id | doaj.art-eb3890ade87f40f9b619ca89709049be |
| institution | Directory Open Access Journal |
| issn | 2047-9980 |
| language | English |
| last_indexed | 2024-04-24T08:52:44Z |
| publishDate | 2024-04-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| spelling | doaj.art-eb3890ade87f40f9b619ca89709049be2024-04-16T09:33:08ZengWileyJournal of the American Heart Association: Cardiovascular and Cerebrovascular Disease2047-99802024-04-0113810.1161/JAHA.123.033053Association Between Young Adult Characteristics and Blood Pressure TrajectoriesJaejin An0Heidi Fischer1Liang Ni2Mengying Xia3Soon Kyu Choi4Kerresa L. Morrissette5Rong Wei6Kristi Reynolds7Paul Muntner8Monika M. Safford9Andrew E. Moran10Brandon K. Bellows11Carmen R. Isasi12Norrina B. Allen13Vanessa Xanthakis14Lisandro D. Colantonio15Yiyi Zhang16Department of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USADepartment of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USADepartment of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USADivision of General Medicine Columbia University Irving Medical Center New York NY USADepartment of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USADepartment of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USADepartment of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USADepartment of Research & Evaluation Kaiser Permanente Southern California Pasadena CA USADepartment of Epidemiology University of Alabama at Birmingham Birmingham AL USADivision of General Internal Medicine Weill Cornell Medicine New York NY USADivision of General Medicine Columbia University Irving Medical Center New York NY USADivision of General Medicine Columbia University Irving Medical Center New York NY USADepartment of Epidemiology and Population Health Albert Einstein College of Medicine Bronx NY USADivision of Epidemiology Northwestern University Chicago IL USADepartment of Medicine Boston University Chobanian and Avedisian School of Medicine Boston MA USADepartment of Epidemiology University of Alabama at Birmingham Birmingham AL USADivision of General Medicine Columbia University Irving Medical Center New York NY USABackground Blood pressure (BP) trajectories from young adulthood through middle age are associated with cardiovascular risk. We examined the associations of hypertension risk factors with BP trajectories among a large diverse sample. Methods and Results We analyzed data from young adults, aged 18 to 39 years, with untreated BP <140/90 mm Hg at baseline from Kaiser Permanente Southern California (N=355 324). We used latent growth curve models to identify 10‐year BP trajectories and to assess the associations between characteristics in young adulthood and BP trajectories. We identified the following 5 distinct systolic BP trajectories, which appeared to be determined mainly by the baseline BP with progressively higher BP at each year: group 1 (lowest BP trajectory, 7.9%), group 2 (26.5%), group 3 (33.0%), group 4 (25.4%), and group 5 (highest BP trajectory, 7.3%). Older age (adjusted odds ratio for 30–39 versus 18–29 years, 1.23 [95% CI, 1.18–1.28]), male sex (13.38 [95% CI, 12.80–13.99]), obesity (body mass index ≥30 versus 18.5–24.9 kg/m2, 14.81 [95% CI, 14.03–15.64]), overweight (body mass index 25–29.9 versus 18.5–24.9 kg/m2, 3.16 [95% CI, 3.00–3.33]), current smoking (1.58 [95% CI, 1.48–1.67]), prediabetes (1.21 [95% CI, 1.13–1.29]), diabetes (1.60 [95% CI, 1.41–1.81]) and high low‐density lipoprotein cholesterol (≥160 versus <100 mg/dL, 1.52 [95% CI, 1.37–1.68]) were associated with the highest BP trajectory (group 5) compared with the reference group (group 2). Conclusions Traditional hypertension risk factors including smoking, diabetes, and elevated lipids were associated with BP trajectories in young adults, with obesity having the strongest association with the highest BP trajectory group.https://www.ahajournals.org/doi/10.1161/JAHA.123.033053blood pressure trajectoriescardiovascular riskhypertensionyoung adults |
| spellingShingle | Jaejin An Heidi Fischer Liang Ni Mengying Xia Soon Kyu Choi Kerresa L. Morrissette Rong Wei Kristi Reynolds Paul Muntner Monika M. Safford Andrew E. Moran Brandon K. Bellows Carmen R. Isasi Norrina B. Allen Vanessa Xanthakis Lisandro D. Colantonio Yiyi Zhang Association Between Young Adult Characteristics and Blood Pressure Trajectories Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease blood pressure trajectories cardiovascular risk hypertension young adults |
| title | Association Between Young Adult Characteristics and Blood Pressure Trajectories |
| title_full | Association Between Young Adult Characteristics and Blood Pressure Trajectories |
| title_fullStr | Association Between Young Adult Characteristics and Blood Pressure Trajectories |
| title_full_unstemmed | Association Between Young Adult Characteristics and Blood Pressure Trajectories |
| title_short | Association Between Young Adult Characteristics and Blood Pressure Trajectories |
| title_sort | association between young adult characteristics and blood pressure trajectories |
| topic | blood pressure trajectories cardiovascular risk hypertension young adults |
| url | https://www.ahajournals.org/doi/10.1161/JAHA.123.033053 |
| work_keys_str_mv | AT jaejinan associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT heidifischer associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT liangni associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT mengyingxia associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT soonkyuchoi associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT kerresalmorrissette associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT rongwei associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT kristireynolds associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT paulmuntner associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT monikamsafford associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT andrewemoran associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT brandonkbellows associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT carmenrisasi associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT norrinaballen associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT vanessaxanthakis associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT lisandrodcolantonio associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories AT yiyizhang associationbetweenyoungadultcharacteristicsandbloodpressuretrajectories |