Synthesis of Glycosidic (β-1′′→6, 3′ and 4′) Site Isomers of Neomycin B and Their Effect on RNA and DNA Triplex Stability

Synthesis of Glycosidic (β-1′′→6, 3′ and 4′) Site Isomers of Neomycin B and Their Effect on RNA and DNA Triplex Stability

Glycosidic (β-1′′→6, 3′ and 4′) site isomers of neomycin B (i.e., neobiosamine (β-1′′→6, 3′ and 4′) neamines) have been synthesized in a straightforward manner. Peracetylated neomyci...

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Bibliographic Details
Main Authors: Lotta Granqvist, Ville Tähtinen, Pasi Virta
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Molecules
Subjects:
aminoglycosides
DNA- and RNA-triple helices
groove binders
Online Access:https://www.mdpi.com/1420-3049/24/3/580

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