The outcome of intravenous and inhalation anesthesia after pancreatic cancer resection: a retrospective study
Abstract Background Different types of anesthesia may affect cancer patient’s outcomes, we compared the overall survival (OS) and disease-free survival (DFS) of patients with pancreatic cancer under total intravenous and inhalation anesthesia. Methods The authors collected the electronic medical rec...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-05-01
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| Series: | BMC Anesthesiology |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s12871-022-01703-8 |
| _version_ | 1818161731067707392 |
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| author | Jie Ren Junli Wang Jingwen Chen Yue Ma Yutong Yang Ming Wei Yu Wang Liping Wang |
| author_facet | Jie Ren Junli Wang Jingwen Chen Yue Ma Yutong Yang Ming Wei Yu Wang Liping Wang |
| author_sort | Jie Ren |
| collection | DOAJ |
| description | Abstract Background Different types of anesthesia may affect cancer patient’s outcomes, we compared the overall survival (OS) and disease-free survival (DFS) of patients with pancreatic cancer under total intravenous and inhalation anesthesia. Methods The authors collected the electronic medical records of patients who had accepted at a pancreatectomy from January 1, 2010 to December 31, 2016. Patients respectively received total intravenous anesthesia (TIVA) or inhalational anesthesia (INHA). Stabilized inverse probability of treatment weighting (SIPTW)was used to minimize differences. Kaplan–Meier survival was established to analyze the influence of sort of anesthesia on disease-free and overall survival. We compare the effects of each sort of anesthesia on cancer recurrence or metastasis and all-cause mortality. Results A total of 463 patients who had undergone pancreatic cancer resection were collected in this study, of which 421 patients were available (TIVA group, n = 114 INHA group, n = 307). After SIPTW there were no significant differences between the two groups in disease-free survival (hazard ratio, 1.01, 95%CI, 0.78 to 1.29, P = 0.959) or overall survival (hazard ratio, 1.11, 95%CI, 0.87 to 1.42, P = 0.405). Conclusions In conclusion, the present study showed no significant difference in overall survival and disease-free survival between total intravenous anesthesia and volatile anesthesia. |
| first_indexed | 2024-12-11T16:22:25Z |
| format | Article |
| id | doaj.art-eb3d8479fc0b4279be98cb216302e5ae |
| institution | Directory Open Access Journal |
| issn | 1471-2253 |
| language | English |
| last_indexed | 2024-12-11T16:22:25Z |
| publishDate | 2022-05-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Anesthesiology |
| spelling | doaj.art-eb3d8479fc0b4279be98cb216302e5ae2022-12-22T00:58:50ZengBMCBMC Anesthesiology1471-22532022-05-012211910.1186/s12871-022-01703-8The outcome of intravenous and inhalation anesthesia after pancreatic cancer resection: a retrospective studyJie Ren0Junli Wang1Jingwen Chen2Yue Ma3Yutong Yang4Ming Wei5Yu Wang6Liping Wang7Department of Anesthesiology, Harbin Medical University Cancer HospitalDepartment of Anesthesiology, Harbin Medical University Cancer HospitalDepartment of Anesthesiology, Harbin Medical University Cancer HospitalDepartment of Anesthesiology, Harbin Medical University Cancer HospitalDepartment of Anesthesiology, Harbin Medical University Cancer HospitalDepartment of Anesthesiology, Harbin Medical University Cancer HospitalDepartment of Anesthesiology, Harbin Medical University Cancer HospitalDepartment of Anesthesiology, Harbin Medical University Cancer HospitalAbstract Background Different types of anesthesia may affect cancer patient’s outcomes, we compared the overall survival (OS) and disease-free survival (DFS) of patients with pancreatic cancer under total intravenous and inhalation anesthesia. Methods The authors collected the electronic medical records of patients who had accepted at a pancreatectomy from January 1, 2010 to December 31, 2016. Patients respectively received total intravenous anesthesia (TIVA) or inhalational anesthesia (INHA). Stabilized inverse probability of treatment weighting (SIPTW)was used to minimize differences. Kaplan–Meier survival was established to analyze the influence of sort of anesthesia on disease-free and overall survival. We compare the effects of each sort of anesthesia on cancer recurrence or metastasis and all-cause mortality. Results A total of 463 patients who had undergone pancreatic cancer resection were collected in this study, of which 421 patients were available (TIVA group, n = 114 INHA group, n = 307). After SIPTW there were no significant differences between the two groups in disease-free survival (hazard ratio, 1.01, 95%CI, 0.78 to 1.29, P = 0.959) or overall survival (hazard ratio, 1.11, 95%CI, 0.87 to 1.42, P = 0.405). Conclusions In conclusion, the present study showed no significant difference in overall survival and disease-free survival between total intravenous anesthesia and volatile anesthesia.https://doi.org/10.1186/s12871-022-01703-8TIVAINHASIPTWPancreatic cancerOverall survivalDisease-free survival |
| spellingShingle | Jie Ren Junli Wang Jingwen Chen Yue Ma Yutong Yang Ming Wei Yu Wang Liping Wang The outcome of intravenous and inhalation anesthesia after pancreatic cancer resection: a retrospective study BMC Anesthesiology TIVA INHA SIPTW Pancreatic cancer Overall survival Disease-free survival |
| title | The outcome of intravenous and inhalation anesthesia after pancreatic cancer resection: a retrospective study |
| title_full | The outcome of intravenous and inhalation anesthesia after pancreatic cancer resection: a retrospective study |
| title_fullStr | The outcome of intravenous and inhalation anesthesia after pancreatic cancer resection: a retrospective study |
| title_full_unstemmed | The outcome of intravenous and inhalation anesthesia after pancreatic cancer resection: a retrospective study |
| title_short | The outcome of intravenous and inhalation anesthesia after pancreatic cancer resection: a retrospective study |
| title_sort | outcome of intravenous and inhalation anesthesia after pancreatic cancer resection a retrospective study |
| topic | TIVA INHA SIPTW Pancreatic cancer Overall survival Disease-free survival |
| url | https://doi.org/10.1186/s12871-022-01703-8 |
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