ADuLT: An efficient and robust time-to-event GWAS
Abstract Proportional hazards models have been proposed to analyse time-to-event phenotypes in genome-wide association studies (GWAS). However, little is known about the ability of proportional hazards models to identify genetic associations under different generative models and when ascertainment i...
Main Authors: | Emil M. Pedersen, Esben Agerbo, Oleguer Plana-Ripoll, Jette Steinbach, Morten D. Krebs, David M. Hougaard, Thomas Werge, Merete Nordentoft, Anders D. Børglum, Katherine L. Musliner, Andrea Ganna, Andrew J. Schork, Preben B. Mortensen, John J. McGrath, Florian Privé, Bjarni J. Vilhjálmsson |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-023-41210-z |
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