Elucidation of drug resistance mutations in Mycobacterium tuberculosis isolates from North India by whole-genome sequencing

Elucidation of drug resistance mutations in Mycobacterium tuberculosis isolates from North India by whole-genome sequencing

Objectives: Rapid diagnosis of drug-resistant tuberculosis (TB) is required for better patient management and treatment outcomes. Whole-genome sequencing (WGS) can be used to detect single nucleotide polymorphisms (SNPs) and deletions/insertions that are responsible for mostMycobacterium tuberculosi...

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Bibliographic Details
Main Authors: Sunil Sethi, Yuhan Hao, Stuart M. Brown, Timothy Walker, Rakesh Yadav, Kamran Zaman, Ashutosh Nath Aggarwal, Digambar Behera
Format: Article
Language:English
Published: Elsevier 2020-03-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Whole-genome sequencing
Tuberculosis
Diagnosis
Drug resistance
Strain typing
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716519301298

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