Free Myocutaneous Flap Assessment in a Rat Model: Verification of a Wireless Bioelectrical Impedance Assessment (BIA) System for Vascular Compromise Following Microsurgery
Background: Microvascular tissue transfer is a common reconstructive procedure. We designed a bioelectrical impedance assessment (BIA) system for quantitative analysis of tissue status. This study attempts to verify it through the animal model. Methods: The flaps of the rat model were monitored by t...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2021-05-01
|
| Series: | Journal of Personalized Medicine |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2075-4426/11/5/373 |
| _version_ | 1797535327291703296 |
|---|---|
| author | Yao-Kuang Huang Min Yi Wong Chi-Rung Wu Yung-Ze Cheng Bor-Shyh Lin |
| author_facet | Yao-Kuang Huang Min Yi Wong Chi-Rung Wu Yung-Ze Cheng Bor-Shyh Lin |
| author_sort | Yao-Kuang Huang |
| collection | DOAJ |
| description | Background: Microvascular tissue transfer is a common reconstructive procedure. We designed a bioelectrical impedance assessment (BIA) system for quantitative analysis of tissue status. This study attempts to verify it through the animal model. Methods: The flaps of the rat model were monitored by the BIA system. Results: The BIA variation of the free flap in the rat after the vascular compromise was recorded. The non-vascular ligation limbs of the same rat served as a control group. The bio-impedance in the experimental group was larger than the control group. The bio-impedances of both the <b>thigh</b>/<b>feet</b> flaps in the experimental group were increased over time. In the <b>thigh</b>, the difference in bio-impedance from the control group was first detected at 10 kHz at the 3rd and last at 1 kHz at the 6th h, after vascular compromise. The same finding was observed in the <b>feet</b>. Compared with the control group, the bio-impedance ratio (1 kHz/20 kHz) of the experimental group decreased with time, while their variation tendencies in the thigh and feet were similar. Conclusions: The flap may be monitored by the BIA for vascular status. |
| first_indexed | 2024-03-10T11:43:52Z |
| format | Article |
| id | doaj.art-eb457180f0a94c989779e1a9971a0b16 |
| institution | Directory Open Access Journal |
| issn | 2075-4426 |
| language | English |
| last_indexed | 2024-03-10T11:43:52Z |
| publishDate | 2021-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Personalized Medicine |
| spelling | doaj.art-eb457180f0a94c989779e1a9971a0b162023-11-21T18:18:57ZengMDPI AGJournal of Personalized Medicine2075-44262021-05-0111537310.3390/jpm11050373Free Myocutaneous Flap Assessment in a Rat Model: Verification of a Wireless Bioelectrical Impedance Assessment (BIA) System for Vascular Compromise Following MicrosurgeryYao-Kuang Huang0Min Yi Wong1Chi-Rung Wu2Yung-Ze Cheng3Bor-Shyh Lin4Division of Thoracic and Cardiovascular Surgery, Chia Yi Chang Gung Memorial Hospital, College of Medicine, Chia-Yi and Chang Gung University, Taoyuan 33302, TaiwanDivision of Thoracic and Cardiovascular Surgery, Chia Yi Chang Gung Memorial Hospital, College of Medicine, Chia-Yi and Chang Gung University, Taoyuan 33302, TaiwanInstitute of Imaging and Biomedical Photonics, National Yang Ming Chiao Tung University, Tainan 71150, TaiwanDepartment of Medical Research, Chi-Mei Medical Center, Tainan 71004, TaiwanInstitute of Imaging and Biomedical Photonics, National Yang Ming Chiao Tung University, Tainan 71150, TaiwanBackground: Microvascular tissue transfer is a common reconstructive procedure. We designed a bioelectrical impedance assessment (BIA) system for quantitative analysis of tissue status. This study attempts to verify it through the animal model. Methods: The flaps of the rat model were monitored by the BIA system. Results: The BIA variation of the free flap in the rat after the vascular compromise was recorded. The non-vascular ligation limbs of the same rat served as a control group. The bio-impedance in the experimental group was larger than the control group. The bio-impedances of both the <b>thigh</b>/<b>feet</b> flaps in the experimental group were increased over time. In the <b>thigh</b>, the difference in bio-impedance from the control group was first detected at 10 kHz at the 3rd and last at 1 kHz at the 6th h, after vascular compromise. The same finding was observed in the <b>feet</b>. Compared with the control group, the bio-impedance ratio (1 kHz/20 kHz) of the experimental group decreased with time, while their variation tendencies in the thigh and feet were similar. Conclusions: The flap may be monitored by the BIA for vascular status.https://www.mdpi.com/2075-4426/11/5/373flap graftingmicrosurgerybiosensorbioelectrical impedancerat |
| spellingShingle | Yao-Kuang Huang Min Yi Wong Chi-Rung Wu Yung-Ze Cheng Bor-Shyh Lin Free Myocutaneous Flap Assessment in a Rat Model: Verification of a Wireless Bioelectrical Impedance Assessment (BIA) System for Vascular Compromise Following Microsurgery Journal of Personalized Medicine flap grafting microsurgery biosensor bioelectrical impedance rat |
| title | Free Myocutaneous Flap Assessment in a Rat Model: Verification of a Wireless Bioelectrical Impedance Assessment (BIA) System for Vascular Compromise Following Microsurgery |
| title_full | Free Myocutaneous Flap Assessment in a Rat Model: Verification of a Wireless Bioelectrical Impedance Assessment (BIA) System for Vascular Compromise Following Microsurgery |
| title_fullStr | Free Myocutaneous Flap Assessment in a Rat Model: Verification of a Wireless Bioelectrical Impedance Assessment (BIA) System for Vascular Compromise Following Microsurgery |
| title_full_unstemmed | Free Myocutaneous Flap Assessment in a Rat Model: Verification of a Wireless Bioelectrical Impedance Assessment (BIA) System for Vascular Compromise Following Microsurgery |
| title_short | Free Myocutaneous Flap Assessment in a Rat Model: Verification of a Wireless Bioelectrical Impedance Assessment (BIA) System for Vascular Compromise Following Microsurgery |
| title_sort | free myocutaneous flap assessment in a rat model verification of a wireless bioelectrical impedance assessment bia system for vascular compromise following microsurgery |
| topic | flap grafting microsurgery biosensor bioelectrical impedance rat |
| url | https://www.mdpi.com/2075-4426/11/5/373 |
| work_keys_str_mv | AT yaokuanghuang freemyocutaneousflapassessmentinaratmodelverificationofawirelessbioelectricalimpedanceassessmentbiasystemforvascularcompromisefollowingmicrosurgery AT minyiwong freemyocutaneousflapassessmentinaratmodelverificationofawirelessbioelectricalimpedanceassessmentbiasystemforvascularcompromisefollowingmicrosurgery AT chirungwu freemyocutaneousflapassessmentinaratmodelverificationofawirelessbioelectricalimpedanceassessmentbiasystemforvascularcompromisefollowingmicrosurgery AT yungzecheng freemyocutaneousflapassessmentinaratmodelverificationofawirelessbioelectricalimpedanceassessmentbiasystemforvascularcompromisefollowingmicrosurgery AT borshyhlin freemyocutaneousflapassessmentinaratmodelverificationofawirelessbioelectricalimpedanceassessmentbiasystemforvascularcompromisefollowingmicrosurgery |