Research Progress on Hyperthermia and Anti-Tumor Immunity

In recent years, with the development of comprehensive tumor therapy, hyperthermia has become one of the important means of cancer treatment. A large number of studies have shown that the removal of tumor cells depends on exogenous treatment methods and the body's own anti-tumor immune status....

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Main Authors: YIN Zhucheng, LIANG Xinjun
Format: Article
Language:zho
Published: Magazine House of Cancer Research on Prevention and Treatment 2022-08-01
Series:Zhongliu Fangzhi Yanjiu
Subjects:
Online Access:http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.22.0320
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author YIN Zhucheng
LIANG Xinjun
author_facet YIN Zhucheng
LIANG Xinjun
author_sort YIN Zhucheng
collection DOAJ
description In recent years, with the development of comprehensive tumor therapy, hyperthermia has become one of the important means of cancer treatment. A large number of studies have shown that the removal of tumor cells depends on exogenous treatment methods and the body's own anti-tumor immune status. Hyperthermia cannot only directly kill tumor cells but also activate the body's immunity to exhibit an anti-tumor effect. In recent years, with the deepening of tumor research, hyperthermia has been able to create a type I tumor microenvironment with PD-L1 overexpression and enrichment of tumor-infiltrating lymphocytes, complementing the enhancement of immune checkpoint inhibitors. Hyperthermia combined with immunotherapy may offer a new perspective in cancer treatment. The mechanism of tumor hyperthermia and anti-tumor immunity and its clinical application have aroused great interest and become a new research field. This article reviews the relationship between tumor hyperthermia and anti-tumor immunity.
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spelling doaj.art-eb45d74ba0774b5481dd334c55ae3ce62022-12-22T04:24:06ZzhoMagazine House of Cancer Research on Prevention and TreatmentZhongliu Fangzhi Yanjiu1000-85782022-08-0149882783110.3971/j.issn.1000-8578.2022.22.03208578.2022.22.0320Research Progress on Hyperthermia and Anti-Tumor ImmunityYIN Zhucheng0LIANG Xinjun1Department of Medical Oncology, Hubei Cancer Hospital, Wuhan 430079, ChinaDepartment of Medical Oncology, Hubei Cancer Hospital, Wuhan 430079, ChinaIn recent years, with the development of comprehensive tumor therapy, hyperthermia has become one of the important means of cancer treatment. A large number of studies have shown that the removal of tumor cells depends on exogenous treatment methods and the body's own anti-tumor immune status. Hyperthermia cannot only directly kill tumor cells but also activate the body's immunity to exhibit an anti-tumor effect. In recent years, with the deepening of tumor research, hyperthermia has been able to create a type I tumor microenvironment with PD-L1 overexpression and enrichment of tumor-infiltrating lymphocytes, complementing the enhancement of immune checkpoint inhibitors. Hyperthermia combined with immunotherapy may offer a new perspective in cancer treatment. The mechanism of tumor hyperthermia and anti-tumor immunity and its clinical application have aroused great interest and become a new research field. This article reviews the relationship between tumor hyperthermia and anti-tumor immunity.http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.22.0320hyperthermiaimmunotherapyanti-tumor immunitycytokine
spellingShingle YIN Zhucheng
LIANG Xinjun
Research Progress on Hyperthermia and Anti-Tumor Immunity
Zhongliu Fangzhi Yanjiu
hyperthermia
immunotherapy
anti-tumor immunity
cytokine
title Research Progress on Hyperthermia and Anti-Tumor Immunity
title_full Research Progress on Hyperthermia and Anti-Tumor Immunity
title_fullStr Research Progress on Hyperthermia and Anti-Tumor Immunity
title_full_unstemmed Research Progress on Hyperthermia and Anti-Tumor Immunity
title_short Research Progress on Hyperthermia and Anti-Tumor Immunity
title_sort research progress on hyperthermia and anti tumor immunity
topic hyperthermia
immunotherapy
anti-tumor immunity
cytokine
url http://www.zlfzyj.com/EN/10.3971/j.issn.1000-8578.2022.22.0320
work_keys_str_mv AT yinzhucheng researchprogressonhyperthermiaandantitumorimmunity
AT liangxinjun researchprogressonhyperthermiaandantitumorimmunity