Efficient data reconstruction: The bottleneck of large-scale application of DNA storage
Summary: Over the past decade, the rapid development of DNA synthesis and sequencing technologies has enabled preliminary use of DNA molecules for digital data storage, overcoming the capacity and persistence bottlenecks of silicon-based storage media. DNA storage has now been fully accomplished in...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-04-01
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| Series: | Cell Reports |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124724000275 |
| _version_ | 1797249183600607232 |
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| author | Ben Cao Yanfen Zheng Qi Shao Zhenlu Liu Lei Xie Yunzhu Zhao Bin Wang Qiang Zhang Xiaopeng Wei |
| author_facet | Ben Cao Yanfen Zheng Qi Shao Zhenlu Liu Lei Xie Yunzhu Zhao Bin Wang Qiang Zhang Xiaopeng Wei |
| author_sort | Ben Cao |
| collection | DOAJ |
| description | Summary: Over the past decade, the rapid development of DNA synthesis and sequencing technologies has enabled preliminary use of DNA molecules for digital data storage, overcoming the capacity and persistence bottlenecks of silicon-based storage media. DNA storage has now been fully accomplished in the laboratory through existing biotechnology, which again demonstrates the viability of carbon-based storage media. However, the high cost and latency of data reconstruction pose challenges that hinder the practical implementation of DNA storage beyond the laboratory. In this article, we review existing advanced DNA storage methods, analyze the characteristics and performance of biotechnological approaches at various stages of data writing and reading, and discuss potential factors influencing DNA storage from the perspective of data reconstruction. |
| first_indexed | 2024-04-24T20:26:26Z |
| format | Article |
| id | doaj.art-eb4a711080b04ca0b48620695458f7d9 |
| institution | Directory Open Access Journal |
| issn | 2211-1247 |
| language | English |
| last_indexed | 2024-04-24T20:26:26Z |
| publishDate | 2024-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Cell Reports |
| spelling | doaj.art-eb4a711080b04ca0b48620695458f7d92024-03-22T05:39:12ZengElsevierCell Reports2211-12472024-04-01434113699Efficient data reconstruction: The bottleneck of large-scale application of DNA storageBen Cao0Yanfen Zheng1Qi Shao2Zhenlu Liu3Lei Xie4Yunzhu Zhao5Bin Wang6Qiang Zhang7Xiaopeng Wei8School of Computer Science and Technology, Dalian University of Technology, Lingshui Street, Dalian, Liaoning 116024, China; Centre for Frontier AI Research, Agency for Science, Technology, and Research (A∗STAR), 1 Fusionopolis Way, Singapore 138632, SingaporeSchool of Computer Science and Technology, Dalian University of Technology, Lingshui Street, Dalian, Liaoning 116024, ChinaKey Laboratory of Advanced Design and Intelligent Computing, Ministry of Education, School of Software Engineering, Dalian University, Xuefu Street, Dalian, Liaoning 116622, ChinaKey Laboratory of Advanced Design and Intelligent Computing, Ministry of Education, School of Software Engineering, Dalian University, Xuefu Street, Dalian, Liaoning 116622, ChinaKey Laboratory of Advanced Design and Intelligent Computing, Ministry of Education, School of Software Engineering, Dalian University, Xuefu Street, Dalian, Liaoning 116622, ChinaKey Laboratory of Advanced Design and Intelligent Computing, Ministry of Education, School of Software Engineering, Dalian University, Xuefu Street, Dalian, Liaoning 116622, ChinaKey Laboratory of Advanced Design and Intelligent Computing, Ministry of Education, School of Software Engineering, Dalian University, Xuefu Street, Dalian, Liaoning 116622, ChinaSchool of Computer Science and Technology, Dalian University of Technology, Lingshui Street, Dalian, Liaoning 116024, China; Corresponding authorSchool of Computer Science and Technology, Dalian University of Technology, Lingshui Street, Dalian, Liaoning 116024, ChinaSummary: Over the past decade, the rapid development of DNA synthesis and sequencing technologies has enabled preliminary use of DNA molecules for digital data storage, overcoming the capacity and persistence bottlenecks of silicon-based storage media. DNA storage has now been fully accomplished in the laboratory through existing biotechnology, which again demonstrates the viability of carbon-based storage media. However, the high cost and latency of data reconstruction pose challenges that hinder the practical implementation of DNA storage beyond the laboratory. In this article, we review existing advanced DNA storage methods, analyze the characteristics and performance of biotechnological approaches at various stages of data writing and reading, and discuss potential factors influencing DNA storage from the perspective of data reconstruction.http://www.sciencedirect.com/science/article/pii/S2211124724000275CP: Molecular biology |
| spellingShingle | Ben Cao Yanfen Zheng Qi Shao Zhenlu Liu Lei Xie Yunzhu Zhao Bin Wang Qiang Zhang Xiaopeng Wei Efficient data reconstruction: The bottleneck of large-scale application of DNA storage Cell Reports CP: Molecular biology |
| title | Efficient data reconstruction: The bottleneck of large-scale application of DNA storage |
| title_full | Efficient data reconstruction: The bottleneck of large-scale application of DNA storage |
| title_fullStr | Efficient data reconstruction: The bottleneck of large-scale application of DNA storage |
| title_full_unstemmed | Efficient data reconstruction: The bottleneck of large-scale application of DNA storage |
| title_short | Efficient data reconstruction: The bottleneck of large-scale application of DNA storage |
| title_sort | efficient data reconstruction the bottleneck of large scale application of dna storage |
| topic | CP: Molecular biology |
| url | http://www.sciencedirect.com/science/article/pii/S2211124724000275 |
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