Anti-inflammatory effect of dental pulp stem cells
Dental pulp stem cells (DPSCs) have received a lot of attention as a regenerative medicine tool with strong immunomodulatory capabilities. The excessive inflammatory response involves a variety of immune cells, cytokines, and has a considerable impact on tissue regeneration. The use of DPSCs for con...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Frontiers Media S.A.
2023-11-01
|
| Series: | Frontiers in Immunology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1284868/full |
| _version_ | 1797501474318581760 |
|---|---|
| author | FenYao Li XinXin Wang Jin Shi ShuTing Wu WenBo Xing Yan He |
| author_facet | FenYao Li XinXin Wang Jin Shi ShuTing Wu WenBo Xing Yan He |
| author_sort | FenYao Li |
| collection | DOAJ |
| description | Dental pulp stem cells (DPSCs) have received a lot of attention as a regenerative medicine tool with strong immunomodulatory capabilities. The excessive inflammatory response involves a variety of immune cells, cytokines, and has a considerable impact on tissue regeneration. The use of DPSCs for controlling inflammation for the purpose of treating inflammation-related diseases and autoimmune disorders such as supraspinal nerve inflammation, inflammation of the pulmonary airways, systemic lupus erythematosus, and diabetes mellitus is likely to be safer and more regenerative than traditional medicines. The mechanism of the anti-inflammatory and immunomodulatory effects of DPSCs is relatively complex, and it may be that they themselves or some of the substances they secrete regulate a variety of immune cells through inflammatory immune-related signaling pathways. Most of the current studies are still at the laboratory cellular level and animal model level, and it is believed that through the efforts of more researchers, DPSCs/SHED are expected to be transformed into excellent drugs for the clinical treatment of related diseases. |
| first_indexed | 2024-03-10T03:18:55Z |
| format | Article |
| id | doaj.art-eb4b437d3a09432d8a1b00fbb5703474 |
| institution | Directory Open Access Journal |
| issn | 1664-3224 |
| language | English |
| last_indexed | 2024-03-10T03:18:55Z |
| publishDate | 2023-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Immunology |
| spelling | doaj.art-eb4b437d3a09432d8a1b00fbb57034742023-11-23T10:08:36ZengFrontiers Media S.A.Frontiers in Immunology1664-32242023-11-011410.3389/fimmu.2023.12848681284868Anti-inflammatory effect of dental pulp stem cellsFenYao LiXinXin WangJin ShiShuTing WuWenBo XingYan HeDental pulp stem cells (DPSCs) have received a lot of attention as a regenerative medicine tool with strong immunomodulatory capabilities. The excessive inflammatory response involves a variety of immune cells, cytokines, and has a considerable impact on tissue regeneration. The use of DPSCs for controlling inflammation for the purpose of treating inflammation-related diseases and autoimmune disorders such as supraspinal nerve inflammation, inflammation of the pulmonary airways, systemic lupus erythematosus, and diabetes mellitus is likely to be safer and more regenerative than traditional medicines. The mechanism of the anti-inflammatory and immunomodulatory effects of DPSCs is relatively complex, and it may be that they themselves or some of the substances they secrete regulate a variety of immune cells through inflammatory immune-related signaling pathways. Most of the current studies are still at the laboratory cellular level and animal model level, and it is believed that through the efforts of more researchers, DPSCs/SHED are expected to be transformed into excellent drugs for the clinical treatment of related diseases.https://www.frontiersin.org/articles/10.3389/fimmu.2023.1284868/fulldental pulp stem cellsinflammationanti-inflammatoryimmune regulationregeneration |
| spellingShingle | FenYao Li XinXin Wang Jin Shi ShuTing Wu WenBo Xing Yan He Anti-inflammatory effect of dental pulp stem cells Frontiers in Immunology dental pulp stem cells inflammation anti-inflammatory immune regulation regeneration |
| title | Anti-inflammatory effect of dental pulp stem cells |
| title_full | Anti-inflammatory effect of dental pulp stem cells |
| title_fullStr | Anti-inflammatory effect of dental pulp stem cells |
| title_full_unstemmed | Anti-inflammatory effect of dental pulp stem cells |
| title_short | Anti-inflammatory effect of dental pulp stem cells |
| title_sort | anti inflammatory effect of dental pulp stem cells |
| topic | dental pulp stem cells inflammation anti-inflammatory immune regulation regeneration |
| url | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1284868/full |
| work_keys_str_mv | AT fenyaoli antiinflammatoryeffectofdentalpulpstemcells AT xinxinwang antiinflammatoryeffectofdentalpulpstemcells AT jinshi antiinflammatoryeffectofdentalpulpstemcells AT shutingwu antiinflammatoryeffectofdentalpulpstemcells AT wenboxing antiinflammatoryeffectofdentalpulpstemcells AT yanhe antiinflammatoryeffectofdentalpulpstemcells |