High frequency of HIV precursor-target-specific B cells in sub-Saharan populations

High frequency of HIV precursor-target-specific B cells in sub-Saharan populations

Summary: HIV gp120 engineered outer domain germline-targeting version 8 (eOD-GT8) was designed specifically to engage naive B cell precursors of VRC01-class antibodies. However, the frequency and affinity of naive B cell precursors able to recognize eOD-GT8 have been evaluated only in U.S. populatio...

Bibliografiset tiedot
Päätekijät:	Flavio Matassoli, Alberto Cagigi, Chen-Hsiang Shen, Amy R. Henry, Timothy S. Johnston, Chaim A. Schramm, Christopher A. Cottrell, Oleksandr Kalyuzhniy, Abby Spangler, Leigh Eller, Merlin Robb, Michael Eller, Prossy Naluyima, Peter D. Kwong, Daniel C. Douek, William R. Schief, Sarah F. Andrews, Adrian B. McDermott
Aineistotyyppi:	Artikkeli
Kieli:	English
Julkaistu:	Elsevier 2023-12-01
Sarja:	Cell Reports
Aiheet:	CP: Immunology CP: Microbiology
Linkit:	http://www.sciencedirect.com/science/article/pii/S2211124723014626

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