Bibliometric analysis of single-cell sequencing researches on immune cells and their application of DNA damage repair in cancer immunotherapy
IntroductionIn recent decades, single-cell sequencing technology has developed rapidly and used widely in various fields of life sciences, especially for the detection of immune cells. A bibliometric analysis of single-cell sequencing research work on immune cells published during the 2011-2021 peri...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2023-01-01
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| Series: | Frontiers in Oncology |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fonc.2023.1067305/full |
| _version_ | 1828037704305082368 |
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| author | Yu Zhao Yuanxun Xiao Zhengbo Hu Ji Wang Zhiguang Xu Yizhang Mo Guojun Qi Kebing Chen Wu Wu Weiying Ma |
| author_facet | Yu Zhao Yuanxun Xiao Zhengbo Hu Ji Wang Zhiguang Xu Yizhang Mo Guojun Qi Kebing Chen Wu Wu Weiying Ma |
| author_sort | Yu Zhao |
| collection | DOAJ |
| description | IntroductionIn recent decades, single-cell sequencing technology has developed rapidly and used widely in various fields of life sciences, especially for the detection of immune cells. A bibliometric analysis of single-cell sequencing research work on immune cells published during the 2011-2021 period should provide new insight on the use of single-cell sequencing.MethodsWe screened 1,460 publications on single-cell sequencing on immune cells according to the publication date, article type, language, and country.ReultsThe United States published the first and largest number of articles, while China’s research started relatively late, but ranked second in the number of publications. T cells were the most commonly studied immune cells by single-cell sequencing, followed by mononuclear macrophages. Cancer biology was the most common field of immune cell research by single-cell sequencing. Single-cell sequencing studies using γδ T cells were mainly in the fields of cancer biology and cell development, and focused over time from cell surface receptor to cell function. Through in-depth analysis of the articles on single-cell sequencing of T cells in the oncology field, our analysis found that immunotherapy and tumor microenvironment were the most popular research directions in recent years.DiscussionThe combination of DNA damage repair and immunotherapy seems to provide a new strategy for cancer therapy. |
| first_indexed | 2024-04-10T16:15:24Z |
| format | Article |
| id | doaj.art-eb5452eb417544ea83726574e71bc4f2 |
| institution | Directory Open Access Journal |
| issn | 2234-943X |
| language | English |
| last_indexed | 2024-04-10T16:15:24Z |
| publishDate | 2023-01-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Oncology |
| spelling | doaj.art-eb5452eb417544ea83726574e71bc4f22023-02-09T17:37:27ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2023-01-011310.3389/fonc.2023.10673051067305Bibliometric analysis of single-cell sequencing researches on immune cells and their application of DNA damage repair in cancer immunotherapyYu Zhao0Yuanxun Xiao1Zhengbo Hu2Ji Wang3Zhiguang Xu4Yizhang Mo5Guojun Qi6Kebing Chen7Wu Wu8Weiying Ma9Department of Hematology, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, ChinaDepartment of Burn & Plastic Surgery, Yuebei People’s Hospital Affiliated to Shantou University Medical College, Shaoguan, Guangdong, ChinaDepartment of Orthopaedics, Yuebei People’s Hospital Affiliated to Shantou University Medical College, Shaoguan, Guangdong, ChinaDepartment of Spine Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaDepartment of Spine Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaDepartment of Spine Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaGuangdong Provincial Key Laboratory of High Technology for Plant Protection, Plant Protection Research Institute, Guangdong Academy of Agricultural Science, Guangzhou, Guangdong, ChinaDepartment of Spine Surgery, The Sixth Affiliated Hospital of Sun Yat-sen University, Guangzhou, Guangdong, ChinaOrthopedics Rehabilitation Department, Guangdong Work Injury Rehabilitation Center, Guangzhou, Guangdong, ChinaDepartment of Anesthesiology, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong, ChinaIntroductionIn recent decades, single-cell sequencing technology has developed rapidly and used widely in various fields of life sciences, especially for the detection of immune cells. A bibliometric analysis of single-cell sequencing research work on immune cells published during the 2011-2021 period should provide new insight on the use of single-cell sequencing.MethodsWe screened 1,460 publications on single-cell sequencing on immune cells according to the publication date, article type, language, and country.ReultsThe United States published the first and largest number of articles, while China’s research started relatively late, but ranked second in the number of publications. T cells were the most commonly studied immune cells by single-cell sequencing, followed by mononuclear macrophages. Cancer biology was the most common field of immune cell research by single-cell sequencing. Single-cell sequencing studies using γδ T cells were mainly in the fields of cancer biology and cell development, and focused over time from cell surface receptor to cell function. Through in-depth analysis of the articles on single-cell sequencing of T cells in the oncology field, our analysis found that immunotherapy and tumor microenvironment were the most popular research directions in recent years.DiscussionThe combination of DNA damage repair and immunotherapy seems to provide a new strategy for cancer therapy.https://www.frontiersin.org/articles/10.3389/fonc.2023.1067305/fullsingle-cell sequencingimmune cellsT cellbibliometric analysisDNA damage repairimmunotherapy |
| spellingShingle | Yu Zhao Yuanxun Xiao Zhengbo Hu Ji Wang Zhiguang Xu Yizhang Mo Guojun Qi Kebing Chen Wu Wu Weiying Ma Bibliometric analysis of single-cell sequencing researches on immune cells and their application of DNA damage repair in cancer immunotherapy Frontiers in Oncology single-cell sequencing immune cells T cell bibliometric analysis DNA damage repair immunotherapy |
| title | Bibliometric analysis of single-cell sequencing researches on immune cells and their application of DNA damage repair in cancer immunotherapy |
| title_full | Bibliometric analysis of single-cell sequencing researches on immune cells and their application of DNA damage repair in cancer immunotherapy |
| title_fullStr | Bibliometric analysis of single-cell sequencing researches on immune cells and their application of DNA damage repair in cancer immunotherapy |
| title_full_unstemmed | Bibliometric analysis of single-cell sequencing researches on immune cells and their application of DNA damage repair in cancer immunotherapy |
| title_short | Bibliometric analysis of single-cell sequencing researches on immune cells and their application of DNA damage repair in cancer immunotherapy |
| title_sort | bibliometric analysis of single cell sequencing researches on immune cells and their application of dna damage repair in cancer immunotherapy |
| topic | single-cell sequencing immune cells T cell bibliometric analysis DNA damage repair immunotherapy |
| url | https://www.frontiersin.org/articles/10.3389/fonc.2023.1067305/full |
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