Escape and Over-Activation of Innate Immune Responses by SARS-CoV-2: Two Faces of a Coin

Escape and Over-Activation of Innate Immune Responses by SARS-CoV-2: Two Faces of a Coin

In the past 20 years, coronaviruses (CoVs), including SARS-CoV-1, MERS-CoV, and SARS-CoV-2, have rapidly evolved and emerged in the human population. The innate immune system is the first line of defense against invading pathogens. Multiple host cellular receptors can trigger the innate immune syste...

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Bibliographic Details
Main Authors: Sameer-ul-Salam Mattoo, Seong-Jun Kim, Dae-Gyun Ahn, Jinjong Myoung
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Viruses
Subjects:
SARS-CoV-2
innate immunity
interferon
inflammasome
Online Access:https://www.mdpi.com/1999-4915/14/3/530

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