Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma
Both leukocytoclastic vasculitis and metastatic pulmonary calcification are conditions that rarely occur during the course of multiple myeloma. We present a multiple myeloma patient that had severe dyspnea due to metastatic pulmonary calcinosis, and ulceronecrotic skin lesions caused by leukocytocla...
| Main Authors: | , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Galenos Publishing House
2012-12-01
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| Series: | Turkish Journal of Hematology |
| Subjects: | |
| Online Access: | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-23600 |
| _version_ | 1797909145923354624 |
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| author | Seçkin Çağırgan Nur Soyer Filiz Vural Güray Saydam Ilgın Yıldırım Şimşir Ayhan Dönmez Taner Akalın Selen Biçeroğlu Murat Tombuloğlu |
| author_facet | Seçkin Çağırgan Nur Soyer Filiz Vural Güray Saydam Ilgın Yıldırım Şimşir Ayhan Dönmez Taner Akalın Selen Biçeroğlu Murat Tombuloğlu |
| author_sort | Seçkin Çağırgan |
| collection | DOAJ |
| description | Both leukocytoclastic vasculitis and metastatic pulmonary calcification are conditions that rarely occur during the course of multiple myeloma. We present a multiple myeloma patient that had severe dyspnea due to metastatic pulmonary calcinosis, and ulceronecrotic skin lesions caused by leukocytoclastic vasculitis. After 3 courses of standarddose chemotherapy all skin and pulmonary lesions disappeared. Autologous peripheral stem cell transplantation was performed and during 1 year of follow-up the patient was in complete remission; after 1 year, laboratory test results indicated disease relapse. Although the patient was treated with bortezomib and dexamethasone, the disease progressed. Non-myeloablative allogeneic stem cell transplantation was performed, but despite of all treatment the patient died due to disease progression. |
| first_indexed | 2024-04-10T11:03:46Z |
| format | Article |
| id | doaj.art-eb5e543a88024297b5c9c18b5ff35db6 |
| institution | Directory Open Access Journal |
| issn | 1308-5263 |
| language | English |
| last_indexed | 2024-04-10T11:03:46Z |
| publishDate | 2012-12-01 |
| publisher | Galenos Publishing House |
| record_format | Article |
| series | Turkish Journal of Hematology |
| spelling | doaj.art-eb5e543a88024297b5c9c18b5ff35db62023-02-15T16:19:31ZengGalenos Publishing HouseTurkish Journal of Hematology1308-52632012-12-0129439740010.5505/tjh.2012.23600TJH-23600Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple MyelomaSeçkin Çağırgan0Nur Soyer1Filiz Vural2Güray Saydam3Ilgın Yıldırım Şimşir4Ayhan Dönmez5Taner Akalın6Selen Biçeroğlu7Murat Tombuloğlu8Ege University, School Of Medicine, Department Of Hematology, İzmir, TurkeyEge University, School Of Medicine, Department Of Hematology, İzmir, TurkeyEge University, School Of Medicine, Department Of Hematology, İzmir, TurkeyEge University, School Of Medicine, Department Of Hematology, İzmir, TurkeyEge University, School Of Medicine, Department Of Hematology, İzmir, TurkeyEge University, School Of Medicine, Department Of Hematology, İzmir, TurkeyEge University, School Of Medicine, Department Of Pathology, İzmir, TurkeyEge University, School Of Medicine, Department Of Radiology, İzmir, TurkeyEge University, School Of Medicine, Department Of Hematology, İzmir, TurkeyBoth leukocytoclastic vasculitis and metastatic pulmonary calcification are conditions that rarely occur during the course of multiple myeloma. We present a multiple myeloma patient that had severe dyspnea due to metastatic pulmonary calcinosis, and ulceronecrotic skin lesions caused by leukocytoclastic vasculitis. After 3 courses of standarddose chemotherapy all skin and pulmonary lesions disappeared. Autologous peripheral stem cell transplantation was performed and during 1 year of follow-up the patient was in complete remission; after 1 year, laboratory test results indicated disease relapse. Although the patient was treated with bortezomib and dexamethasone, the disease progressed. Non-myeloablative allogeneic stem cell transplantation was performed, but despite of all treatment the patient died due to disease progression.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-23600multiple myelomametastatic calcificationleukocytoclastic vasculitis |
| spellingShingle | Seçkin Çağırgan Nur Soyer Filiz Vural Güray Saydam Ilgın Yıldırım Şimşir Ayhan Dönmez Taner Akalın Selen Biçeroğlu Murat Tombuloğlu Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma Turkish Journal of Hematology multiple myeloma metastatic calcification leukocytoclastic vasculitis |
| title | Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma |
| title_full | Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma |
| title_fullStr | Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma |
| title_full_unstemmed | Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma |
| title_short | Metastatic Pulmonary Calcinosis and Leukocytoclastic Vasculitis in a Patient with Multiple Myeloma |
| title_sort | metastatic pulmonary calcinosis and leukocytoclastic vasculitis in a patient with multiple myeloma |
| topic | multiple myeloma metastatic calcification leukocytoclastic vasculitis |
| url | https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tjh&un=TJH-23600 |
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