Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria.

Mieap, a p53-inducible protein, controls mitochondrial quality by repairing or eliminating unhealthy mitochondria.

Maintenance of healthy mitochondria prevents aging, cancer, and a variety of degenerative diseases that are due to the result of defective mitochondrial quality control (MQC). Recently, we discovered a novel mechanism for MQC, in which Mieap induces intramitochondrial lysosome-like organella that pl...

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Bibliographic Details
Main Authors: Noriaki Kitamura, Yasuyuki Nakamura, Yuji Miyamoto, Takafumi Miyamoto, Koki Kabu, Masaki Yoshida, Manabu Futamura, Shizuko Ichinose, Hirofumi Arakawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3022033?pdf=render

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