Immunogenicity and Therapeutic Efficacy of a Sendai-Virus-Vectored HSV-2 Vaccine in Mouse and Guinea Pig Models

Immunogenicity and Therapeutic Efficacy of a Sendai-Virus-Vectored HSV-2 Vaccine in Mouse and Guinea Pig Models

Background: To date, there is no licensed vaccine for preventing herpes simplex virus type 2 (HSV-2). The current treatment to address the infection and prevent its transmission is not always satisfactory. Methods: We constructed two recombinant vectors, one encoding HSV-2 glycoprotein D (gD, SeV-dF...

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Bibliographic Details
Main Authors:	Xiuxiu Ren, Wenhao Su, Shishi Li, Tingting Zhao, Qiufang Huang, Yinan Wang, Xiaojie Wang, Xiaohuan Zhang, Jiangbo Wei
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Vaccines
Subjects:	herpes simplex virus type 2 Sendai virus vector therapeutic vaccine animal models
Online Access:	https://www.mdpi.com/2076-393X/11/12/1752

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